Protein Info for DVU1164 in Desulfovibrio vulgaris Hildenborough JW710

Name: amiE
Annotation: aliphatic amidase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00795: CN_hydrolase
  • amino acids 18 to 267 (250 residues), 119.7 bits, E=7e-39

Best Hits

Swiss-Prot: 100% identical to AMIF_DESVV: Formamidase (amiF) from Desulfovibrio vulgaris subsp. vulgaris (strain DP4)

KEGG orthology group: K01455, formamidase [EC: 3.5.1.49] (inferred from 100% identity to dvu:DVU1164)

Predicted SEED Role

"Formamidase amiF (EC 3.5.1.49)" (EC 3.5.1.49)

MetaCyc Pathways

• cyanide detoxification II (1/2 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Nitrogen metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.49

Sequence Analysis Tools

See Q72CW9 at UniProt or InterPro

Protein Sequence (334 amino acids)

>DVU1164 aliphatic amidase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MGSIGSMNKPSEGMLMGLVQYPVPIVNSRRDIEASVDRICAATAATKAGYPGMDLIVWPE
YSTQGLNTKKWVTEEFLMDVEEPLFQRYAQTCKENDVWGVFSIMERNPNKNQMPYNTAVI
FNNKGELALKYRKLNPWVPIEPWMPGDLGQPVCDGPGGSKLSLCICHDGMFPEQAREAAY
KGCNVYIRISGYSTQVNEQWILTNRSNAWHNLMYTAAVNLAGYDGVFYYFGEGQVCNFDG
TTLVQGHRNPWEIVTAEVFPKMADQARTDWGLENNIFNVGTRGYVAHPGGVKDCPYTWVK
DFAAGKYHLPWEDKIKIKDGSIYGYPTTGGRFGL