Protein Info for DVU1041 in Desulfovibrio vulgaris Hildenborough JW710

Name: tatC
Annotation: Sec-independent protein translocase TatC (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 257 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 62 to 89 (28 residues), see Phobius details amino acids 101 to 128 (28 residues), see Phobius details amino acids 148 to 175 (28 residues), see Phobius details amino acids 188 to 204 (17 residues), see Phobius details amino acids 210 to 230 (21 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 3 to 220 (218 residues), 228.9 bits, see alignment E=3.5e-72 PF00902: TatC" amino acids 5 to 215 (211 residues), 249.8 bits, see alignment E=1.1e-78

Best Hits

Swiss-Prot: 51% identical to TATC_DESAH: Sec-independent protein translocase protein TatC (tatC) from Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2)

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 100% identity to dvu:DVU1041)

MetaCyc: 38% identical to twin arginine protein translocation system - TatC protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72D88 at UniProt or InterPro

Protein Sequence (257 amino acids)

>DVU1041 Sec-independent protein translocase TatC (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTLLDHLGELRVRLVRCLIAVGLAFAGCYSFAEKLFDLLMQPLVKAMPPDSKLIFTALPE
AFFVYMQVGLVAATFVASPFIFYQIWAFISPGLYEEEKKNAIPIALFSASFFIGGAAFCY
FQVFPYAFEFFMGFATDRILPMPSLSEYLGFALKMLLAFGIIFEMPLFTFFLAKLGILTA
GMMRRGRKYAILGIFIVAAILTPPDVFSQMLMACPMLVLYEISIFIAAAVGRKEKTDEEE
DGDADEATPDERPEQGH