Protein Info for DVU1026 in Desulfovibrio vulgaris Hildenborough JW710

Name: uraA
Annotation: uracil permease (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 44 to 60 (17 residues), see Phobius details amino acids 67 to 83 (17 residues), see Phobius details amino acids 89 to 109 (21 residues), see Phobius details amino acids 121 to 146 (26 residues), see Phobius details amino acids 162 to 179 (18 residues), see Phobius details amino acids 186 to 209 (24 residues), see Phobius details amino acids 231 to 253 (23 residues), see Phobius details amino acids 309 to 330 (22 residues), see Phobius details amino acids 337 to 358 (22 residues), see Phobius details amino acids 370 to 386 (17 residues), see Phobius details amino acids 392 to 410 (19 residues), see Phobius details PF00860: Xan_ur_permease" amino acids 20 to 386 (367 residues), 275.1 bits, see alignment E=4.2e-86 TIGR00801: uracil-xanthine permease" amino acids 20 to 409 (390 residues), 342.6 bits, see alignment E=1.7e-106

Best Hits

Swiss-Prot: 44% identical to PYRP_BACSU: Uracil permease (pyrP) from Bacillus subtilis (strain 168)

KEGG orthology group: K02824, uracil permease (inferred from 100% identity to dvl:Dvul_1967)

Predicted SEED Role

"Uracil permease" in subsystem De Novo Pyrimidine Synthesis or Pyrimidine utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72DA3 at UniProt or InterPro

Protein Sequence (419 amino acids)

>DVU1026 uracil permease (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTTDPRFIPEYNFRFRDGLIGAQMLFVAFGALVLVPLLTGLDPNVALFAAGCATLIFQAI
TRGKVPIFLASSFAFIAPIIYGVQTWGIPGTLCGLTAAGLVYMALSALIRVQGPGVVERV
LPPIVTGPVIMVIGLILSPVAVFMAIGKTGDGAVQLIPKDKAMIVAMVSLASTVIASLLG
RGFVKLIPIFCGIVAGYATSLFFGIVDFTPVLKAPWFAVPNFVTPEWNLDAILFIVPVAI
APAIEHVGGILAIGSVTGKNYLEDPGIDRTLFADSIATMVATSVGGPPCTTYAEVTGAIA
LTRAFNPAILTWAAITAVCLAFVGKLGALLTTIPSPVMGGIMVLLFGAITVVGMNSLVRA
GQDLMVPRNMAVVAIILVFGLGGMAFNVGEFSLQGIGLAGITGVLLNLVLPGRRAASGR