Protein Info for DVU0941 in Desulfovibrio vulgaris Hildenborough JW710

Name: pep*
Annotation: metalloprotease, iron-related (Dmitry Rodionov)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 964 PF00675: Peptidase_M16" amino acids 55 to 144 (90 residues), 31.1 bits, see alignment E=4.2e-11 PF05193: Peptidase_M16_C" amino acids 199 to 377 (179 residues), 66.3 bits, see alignment E=6.7e-22 PF08367: M16C_assoc" amino acids 454 to 703 (250 residues), 230.4 bits, see alignment E=4e-72 PF22516: PreP_C" amino acids 775 to 945 (171 residues), 183.2 bits, see alignment E=6.8e-58

Best Hits

KEGG orthology group: K06972, (no description) (inferred from 100% identity to dvu:DVU0941)

Predicted SEED Role

"peptidase, M16 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72DI8 at UniProt or InterPro

Protein Sequence (964 amino acids)

>DVU0941 metalloprotease, iron-related (Dmitry Rodionov) (Desulfovibrio vulgaris Hildenborough JW710)
MQLHGFELIDETNLEELSSRVRRWRHVVTGAQLLSFCNADENKVFGVSFRTPPGDSTGVA
HILEHSVLCGSERYPVKEPFVELLKGSLQTFLNAFTYPDKTCYPVASTNLQDFRNLVDVY
LDAVFFPRIDENIFRQEGWHIDAETADGPWNYKGVVYNEMKGVYSSPESVLSEQSQQAIF
PEHVYGLDSGGNPERILELTYEQFRDFHRRFYHPGNGRFFFWGDDPEEARLEHIGRVLSR
FDRLDVDSAVPLMGHRDTPRLLEVPFAAGEGDTRGMVTVNWLLDETVDAERNFALHMLEH
ILLGMPGSPLRRALIESGLGEDVAGVGLEAELRQMYFSVGLKGIDPADAERVEVLVMDTL
ASLAEEGVPSDAIEAAFNSVEFSLRENNTGRYPRGLAVMVRSLTTWLYDGDPLALLAFEK
PLAAIRDAIAAGGYFEALIRRCFLDNAHRATVSLVPDMTLEARREEAENKRIEKVQSALS
PSDREAVVSLAATLRALQEAPDSPEALATIPRLGLEDLARENRPIPIEERTSGDVTVLFH
DIDTSGIVYSELLFDLSAVPARLLPLVPLFGRALLEMGTARHDFVALGMRIAAKTGGIEA
DTLFATTRAGRKPVAHMVVSGKATRDNAAALVDIMHEVLHEALFDDAERFGRMVLEEKAR
QEHSLVPSGHGVVSSRLRASFSMAGWLDEVTGGITYLMALRELAERVRDDWQGVRDDLET
LRTLVLRRSGALCNLTADSATAAVAMPLFDGLVAGLPDTAADAVVWAPDALPAAEALVVP
AQVNYVGKGANLYDLGYAYHGSVSVVLKHLRMAFLWDRVRVQGGAYGAFCAFDRMSGAFT
QVSYRDPNVERTLDVYDKCAEYLRTVELDDAALTSAIVGAIGDLDMHMLPDARGEASMLR
HLTGDTEDVRQTMREQMLATTQRHFREFADVLDAVARTGRVCVLGGGSLDAVAATRGWQA
LRVL