Protein Info for DVU0940 in Desulfovibrio vulgaris Hildenborough JW710

Name: pleD
Annotation: GGDEF domain protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 48 to 69 (22 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 76 to 241 (166 residues), 190 bits, see alignment E=1.3e-60 PF00990: GGDEF" amino acids 81 to 238 (158 residues), 170.8 bits, see alignment E=1.1e-54

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU0940)

Predicted SEED Role

"GGDEF/response regulator receiver domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72DI9 at UniProt or InterPro

Protein Sequence (243 amino acids)

>DVU0940 GGDEF domain protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MPERSHRRLVHLAFRMLQGAALGAGAPLGWLVIRTLLDLSPSHPDYDFWLFLYISVGSIL
VFTGMGGWVGREELRLERLSLVDPLTGLYNRRSFETALEKEMARWRRREAPVALLMLDLD
HFKLVNDTWGHQAGDRVLQTLARLLSSTVRIEDLPARVGGEEFAVIMPEVTGDEAYQAAE
RLRLVVAGHLFDIGVESIEVRVSIGVACTEMQNVADGATLVRLADEALYRAKQRGRDRVE
TAW