Protein Info for DVU0813 in Desulfovibrio vulgaris Hildenborough JW710

Name: hrcA
Annotation: heat-inducible transcription repressor HrcA (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 355 TIGR00331: heat-inducible transcription repressor HrcA" amino acids 6 to 347 (342 residues), 259.3 bits, see alignment E=3.6e-81 PF01628: HrcA" amino acids 108 to 333 (226 residues), 170.4 bits, see alignment E=2.9e-54

Best Hits

Swiss-Prot: 100% identical to HRCA_DESVH: Heat-inducible transcription repressor HrcA (hrcA) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K03705, heat-inducible transcriptional repressor (inferred from 100% identity to dvl:Dvul_2164)

Predicted SEED Role

"Heat-inducible transcription repressor HrcA" in subsystem Heat shock dnaK gene cluster extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72DW6 at UniProt or InterPro

Protein Sequence (355 amino acids)

>DVU0813 heat-inducible transcription repressor HrcA (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSALGSRETHVLTTIIESYITSAAPVGSRTVSRRSGLALSPASMRNTMSDLTDMGFLEQP
HTSAGRIPTPKAFRLYVDALLRQSARRDEAPLHMVEALHGHEPEVGALLRRASNLVSEHA
RQVSMVLAPGPAEARLRSLDFVPAGEGLVLAVLVLEGGMVRTRLVRDDTHFGSDELVRFG
NYINAHYRGHTLSGIRNSIHHELSGGGAQLEAMCAQALALGSLALDSIDDDRELYVNGTR
NILDQAEFAELGRMRELMDALEERSRLLELLDRTILEDDVHVTFYPDDVSGGAQRRAPDG
LRGCSMVSAPYGGASPLGVIGVIGPVRMDYRKVLPLVGAVSRVLTQLLRERFATG