Protein Info for SO4733 in Shewanella oneidensis MR-1

Name: lypA
Annotation: lysophospholipase L2 (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 329 PF12146: Hydrolase_4" amino acids 48 to 302 (255 residues), 208.4 bits, see alignment E=2e-65 PF00561: Abhydrolase_1" amino acids 53 to 302 (250 residues), 83.5 bits, see alignment E=4e-27 PF12697: Abhydrolase_6" amino acids 69 to 299 (231 residues), 53.2 bits, see alignment E=1.3e-17 PF00326: Peptidase_S9" amino acids 73 to 164 (92 residues), 28.9 bits, see alignment E=1.6e-10

Best Hits

KEGG orthology group: K01048, lysophospholipase [EC: 3.1.1.5] (inferred from 100% identity to son:SO_4733)

Predicted SEED Role

"Lysophospholipase L2 (EC 3.1.1.5)" in subsystem Synechocystis experimental or Triacylglycerol metabolism (EC 3.1.1.5)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.5

Use Curated BLAST to search for 3.1.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E8D2 at UniProt or InterPro

Protein Sequence (329 amino acids)

>SO4733 lysophospholipase L2 (NCBI ptt file) (Shewanella oneidensis MR-1)
MSQTPSVFSTEHDLNTSEQQAFWQTVVQDTLNTPDGLTLAYMMVKHPKAHASIVISSGRV
ESYLKYQELIFDLYQQGYSVFAIDHRGQGLSSRMTANPHQGHVRRFNDYIDDFALFMQTV
VLKHATSPLFLLGHSMGGAIGTLYLKQHPDVFTAAVFSAPMYGIKLPMPKGFVRWLASKL
DTSLNGGEPNYVLSGQNYKAVPVPFKGNDLTHCQSRYQAYRELYEAAPKLQLGSPTNRWL
TESLDAADACVLATTHIRTPILILQAGEDKIVDNAAQNLAVSSNCQLKVIAGAAHEIFME
KDSYRNQALNYALDFFKRYATRDVDKQAV