Protein Info for SO4638 in Shewanella oneidensis MR-1

Annotation: sensor histidine kinase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 145 to 167 (23 residues), see Phobius details PF00512: HisKA" amino acids 222 to 287 (66 residues), 40.3 bits, see alignment E=1.3e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_4638)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E8M5 at UniProt or InterPro

Protein Sequence (430 amino acids)

>SO4638 sensor histidine kinase (NCBI ptt file) (Shewanella oneidensis MR-1)
MAKVTDSSPKPLPSLYKKIRLTFLALTSLMFAIFWGLIYIAEEQIEVISLEHKLATETRE
YQKNYQRFGDKAQLPDIHELTTYWSKEFVPQWLQAYQQTGFYEHQLGAEDKHFLISPHPS
GQGLLYVVFKDDADDFLDGYEDRLHILISLFGVGLLLFIMAYGLYFVRLLSAPFFEIERK
INALTPEEPSFIPSTPYRETRHIEQTLLENKTKIAAYFTREQEFSRFASHELRTPIMVIQ
GSTELLKKLPNSANEAQQRIANKAIARIDYAGQQMKTLTETFLLLGKEQIESQHYDQVDL
AARLTQLLSEMAQHFAKHEIRHQLSVNQNTAICAPVSFVDIVIGNLIKNAFNYSSGDIEI
TLKNNQLTIKNPLSHHSAEPTGYGCGLIIIERICERMGWHFSAQSLGDDYLATIQFMDNR
EPQQHLNESA