Protein Info for SO4408 in Shewanella oneidensis MR-1

Name: bipA
Annotation: virulence regulator BipA (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 603 PF00009: GTP_EFTU" amino acids 4 to 194 (191 residues), 194.6 bits, see alignment E=3.1e-61 TIGR00231: small GTP-binding protein domain" amino acids 5 to 134 (130 residues), 87.6 bits, see alignment E=8.1e-29 TIGR01394: GTP-binding protein TypA/BipA" amino acids 5 to 599 (595 residues), 967.1 bits, see alignment E=2.8e-295 PF01926: MMR_HSR1" amino acids 8 to 129 (122 residues), 25.3 bits, see alignment E=3.5e-09 PF03144: GTP_EFTU_D2" amino acids 219 to 289 (71 residues), 43.1 bits, see alignment E=1.2e-14 PF00679: EFG_C" amino acids 395 to 476 (82 residues), 79.4 bits, see alignment E=4.1e-26 PF21018: BipA_C" amino acids 485 to 593 (109 residues), 154.3 bits, see alignment E=2.2e-49

Best Hits

Swiss-Prot: 77% identical to TYPA_ECO57: GTP-binding protein TypA/BipA (typA) from Escherichia coli O157:H7

KEGG orthology group: K06207, GTP-binding protein (inferred from 100% identity to son:SO_4408)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E978 at UniProt or InterPro

Protein Sequence (603 amino acids)

>SO4408 virulence regulator BipA (NCBI ptt file) (Shewanella oneidensis MR-1)
MLENLRNIAIIAHVDHGKTTLVDKLLSQSGTLATRGEATERVMDSNDLEKERGITILAKN
TAIKWNDYRINIVDTPGHADFGGEVERVLSMVDSVLLLVDAVDGPMPQTRFVTKKAFAQG
LKPIVVINKIDRPGARPDWVIDQVFDLFDNLGATDEQLDFPIVYASALNGFATLDPDVVS
EDMTPLFQTIVEKVSSPDADADGPFQMQISQLDYNSYVGVIGVGRINRGSIKTNQQVSVI
GADGKVRNGKMGQVLGYMGLERTEVDVANAGDIVAITGLGELKISDTVCAAGNVEAMPPL
SVDEPTLTMTFQVNTSPFAGKEGKYVTSRNILERLQQELVHNVALRVEETDSPDRFAVSG
RGELHLSILIENMRREGYELAVSRPEVILKTIDGELCEPFETLTVDVEEEHQGTVIEKLG
IRKAEMKDMQLDGKGRVRVDFVIPSRGLIGFQTEFLTATSGTGLIYHSFDHYGPHKGGDI
GQRANGVLISNATGKALTFALFGLQDRGRLFIGHAAEVYEGQVVGIHARSNDLTVNCLKG
KQLTNMRASGTDEAQVLTTPITLTLEQALEFIDDDELVEVTPKSIRVRKKHLTENDRKRA
SRG