Protein Info for SO4405 in Shewanella oneidensis MR-1

Name: katG-2
Annotation: catalase/peroxidase HPI (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 728 TIGR00198: catalase/peroxidase HPI" amino acids 10 to 727 (718 residues), 1263.3 bits, see alignment E=0 PF00141: peroxidase" amino acids 83 to 397 (315 residues), 145.6 bits, see alignment E=1.1e-46 amino acids 406 to 702 (297 residues), 99.9 bits, see alignment E=1.1e-32

Best Hits

Swiss-Prot: 100% identical to KATG1_SHEON: Catalase-peroxidase 1 (katG1) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K03782, catalase/peroxidase [EC: 1.11.1.6 1.11.1.7] (inferred from 80% identity to fbl:Fbal_1689)

Predicted SEED Role

"Catalase (EC 1.11.1.6) / Peroxidase (EC 1.11.1.7)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) or Auxin degradation (EC 1.11.1.6, EC 1.11.1.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6, 1.11.1.7

Use Curated BLAST to search for 1.11.1.6 or 1.11.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E981 at UniProt or InterPro

Protein Sequence (728 amino acids)

>SO4405 catalase/peroxidase HPI (NCBI ptt file) (Shewanella oneidensis MR-1)
MDKTQRSQGKCPVMHGANSAVASNNMDWWPKALNLDILHQHDQKTDPMDPNFSYRDAFNS
LDLAAVKQDLHSLMTDSQDWWPADWGHYGGLMIRMAWHSAGTYRIADGRGGAGTGNQRFA
PLNSWPDNANLDKARRLLWPIKKKYGNKLSWADLIILAGNVAYESMGLKTFGFAGGRADI
WHPEKDIYWGSEKQWLAPSDNPNSRYSGARDLENPLAAVMMGLIYVNPEGVDGKPDPLRT
AQDVRITFARMAMDDEETVALTAGGHTVGKCHGNGKAQDLGPEPEGEDVEAQGLGWLNKK
GRGVGCDAVTSGLEGAWTTHPTQWDNGYFYLLLNYDWELKKSPAGAWQWEPINIKEEDKV
ISVGDPAKKFNPIMTDADMAMKIDPEYRKISERFYQDPAYFSEVFARAWFKLTHRDLGPK
SRYLGPEVPSEELIWQDPIPSVDYRLVASEIVELKAKLLASGLSVSELVATAWDSARTFR
GSDFRGGANGARIRLAPQKDWSGNEPERLQKVLKVLSALQASLSKKVSIADLIVLGGAAA
IEKAAHAAGVNITVPFMPGRGDATKEMTDVESFVVLEPLHDAYRNWLKQDYVVQPEEMML
DRSQLMGLTAHEMTVLIGGMRVLGTNHGGTRHGVFTDKVGVLSNDFFVNLTDMAYSWKPV
GTNLYEVVERKTGTVKWTATRVDLVFGSNSVLRVYAEVYAQDDAKEKFVHDFVAAWTKVM
NADRFDLA