Protein Info for SO4318 in Shewanella oneidensis MR-1

Name: rtxB
Annotation: toxin secretion ATP-binding protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 726 transmembrane" amino acids 176 to 198 (23 residues), see Phobius details amino acids 206 to 226 (21 residues), see Phobius details amino acids 282 to 306 (25 residues), see Phobius details amino acids 312 to 329 (18 residues), see Phobius details amino acids 397 to 416 (20 residues), see Phobius details amino acids 422 to 441 (20 residues), see Phobius details TIGR03375: type I secretion system ATPase" amino acids 23 to 715 (693 residues), 929.5 bits, see alignment E=6.1e-284 PF03412: Peptidase_C39" amino acids 24 to 142 (119 residues), 23.1 bits, see alignment E=1.1e-08 PF00664: ABC_membrane" amino acids 177 to 436 (260 residues), 62.4 bits, see alignment E=1.1e-20 PF00005: ABC_tran" amino acids 505 to 654 (150 residues), 112.9 bits, see alignment E=3.9e-36

Best Hits

KEGG orthology group: K06148, ATP-binding cassette, subfamily C, bacterial (inferred from 100% identity to son:SO_4318)

Predicted SEED Role

"Type I secretion system ATPase, LssB family LapB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8E9G5 at UniProt or InterPro

Protein Sequence (726 amino acids)

>SO4318 toxin secretion ATP-binding protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MPVTASEKVEQWTISASQRVIVDPLLDCLVLLTEHFGNPCSSDSLAAGLPLSGAVLTPDL
LPQAASRAGLAAKLSRKGLNEISPILLPCILLLKDKKACILREFDLESDRAVIQLPETGG
EEILTIESLETLYVGYLFLVKQEYRGDMGFDVYLHDNKTHWLVQTLKDSAPIYRDALIAS
VLVNIFALVSPLFIMNVYDKVVPNLAFDSLWVLAIGASIAYLFDLVMRQLRSYLIDVAGK
KVDIIVSSRLFAKAIGIPLEKRSPSIGGMAKQLGEFDSIREILTSATITTLVDLPFALFF
LIVIYIVAGDLAVIPVVGGMIIIGFTLYTQPKLKAAIEEGNKFSSLKHGHLIESLSALES
IKANGAEGIVQKSWQQMIGHSANWQLKSKKLSNSVSNTANFIVQFTVVCVVILGVYRVSD
NLISMGGIIAAVMLSSRAIAPMAQLAGLMTRANHTASALRQLNELMLQEDEFENKGHLVS
KQRLIGKINADHVGFSYPGSEKPVLHPLSLTINPGERIAIIGRNGSGKSTLAKLLVGLFQ
PTTGSLRYDGVDSAQIHPSDLRRNFGYLPQDVTLFHGTIRDNILFGTRQVTEHQLIRAVQ
LSGVSQFTHLEAEGLDQQVGEGGMSLSRGQRQTVALARATLNDPPVLLMDEPTASLDARA
EQQFIRSMQNVSKDRTLLLITHKMHLLQLVDRIIVLERGHVVADGPKAEVLEKLNFGLVN
GGAKNE