Protein Info for SO4017 in Shewanella oneidensis MR-1

Annotation: transglycosylase, Slt family (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01464: SLT" amino acids 121 to 223 (103 residues), 66.8 bits, see alignment E=2.6e-22 PF01476: LysM" amino acids 342 to 382 (41 residues), 54 bits, see alignment 2.5e-18 amino acids 433 to 475 (43 residues), 50.1 bits, see alignment 4.3e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_4017)

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-)" (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EA91 at UniProt or InterPro

Protein Sequence (477 amino acids)

>SO4017 transglycosylase, Slt family (NCBI ptt file) (Shewanella oneidensis MR-1)
MRKTFRQPHALAAMVIAMLMAQLSGCATTSAQTSPTEFGAGLPEAEDHSESAEPQSVEAE
VIDERYADVWEKIQHARTIDVHDDAEVRKQRNFFDDKQKFMTQVTQRAEPFLYYIVSQLE
ARNMPLELALLPIVESGYNPLAQANGPAGLWQMIPATGRNFGLTINSAYDGRKDALASTD
AVLDYLQHLYNTLGNDWINAVAGYNSGELVIKAAIDRNKAKGKPTDFWSLNIPARQVQTV
PKWLAFIQIIREPSHYNLKVMPIANRPFLERLPAPNGVEISQIANAAGLTKAEFKTYNPG
YRQSVIPSKGKYQIALPIENIGHYQENQHKLYAQKRYDSQTYIVKSGDSLGTIAAKFDLS
VKELKQANNLTSDRLKIGQELTLLTPMAANDNEPEPVKTKANTDKSSTKANASSTKATSS
KSTDKPVAKAKTYKVKSGDSLDKIARKSKVKLADLMKWNQLNAKSIIKPGQELKISE