Protein Info for SO3871 in Shewanella oneidensis MR-1

Annotation: thiol:disulfide interchange protein, DsbA family (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF13462: Thioredoxin_4" amino acids 37 to 190 (154 residues), 23.4 bits, see alignment E=6.1e-09

Best Hits

KEGG orthology group: K03673, thiol:disulfide interchange protein DsbA (inferred from 100% identity to son:SO_3871)

Predicted SEED Role

"Periplasmic thiol:disulfide interchange protein, DsbA-like" in subsystem Periplasmic disulfide interchange

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EAM7 at UniProt or InterPro

Protein Sequence (203 amino acids)

>SO3871 thiol:disulfide interchange protein, DsbA family (NCBI ptt file) (Shewanella oneidensis MR-1)
MKKSLIVITTSLLMSFGAHAATEGVEYQVLPKAIQFDAPNQVVKIYSINCPFCYKYEKAG
IPNVKIIPAGMSFEQYHITTKPPFGIEKSTALAIAKVVKGDSVFKELKNKYYEQYHVKKE
KFKDSDSAIAYSLDILSMSRAEFDSHAKDPAVKALLAKWDLGVEVAKIQGIPAITVNGKY
LINTKSISSMEVLKELIAELSDK