Protein Info for SO3804 in Shewanella oneidensis MR-1

Name: ubiX
Annotation: phenylacrylic acid decarboxylase, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02441: Flavoprotein
  • amino acids 9 to 197 (189 residues), 136.9 bits, E=2.4e-44
• TIGR00421: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases
  • amino acids 11 to 207 (197 residues), 181.6 bits, E=6e-58

Best Hits

KEGG orthology group: K03186, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiX [EC: 4.1.1.-] (inferred from 100% identity to son:SO_3804)

Predicted SEED Role

"3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX (EC 4.1.1.-)" in subsystem Ubiquinone Biosynthesis (EC 4.1.1.-)

MetaCyc Pathways

• superpathway of chorismate metabolism (50/59 steps found)
• superpathway of ubiquinol-8 biosynthesis (early decarboxylation) (11/12 steps found)
• ubiquinol-8 biosynthesis (early decarboxylation) (7/8 steps found)

KEGG Metabolic Maps

• 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
• 1- and 2-Methylnaphthalene degradation
• 3-Chloroacrylic acid degradation
• Ascorbate and aldarate metabolism
• Benzoate degradation via hydroxylation
• Biphenyl degradation
• Fluorene degradation
• Phenylalanine metabolism
• Phenylpropanoid biosynthesis
• Purine metabolism
• Pyruvate metabolism
• Tryptophan metabolism
• Tyrosine metabolism
• Ubiquinone and menaquinone biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.-

Use Curated BLAST to search for 4.1.1.-

Sequence Analysis Tools

See Q8EAT8 at UniProt or InterPro

Protein Sequence (219 amino acids)

>SO3804 phenylacrylic acid decarboxylase, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MAYAKSSKAISLAWTGASGAPYGLKLLECLLASGYQVFLMISSAARVVLATEHGLQLSAN
SDKAKAQLLDVLAQKNIPLSGELVVLGKDEWFSPPASGSAAPKQMVICPCSTGTLAAVAT
GMSNNLLERAADVVLKERGQLILVPRETPFNAIHLEHMLNLSRLGATIMPAAPGFYHNPK
SVEDLIDFMVARILDHLGVDHALTSRWGYDKHSPNDIDN