Protein Info for SO3562 in Shewanella oneidensis MR-1

Annotation: proton/glutamate symporter, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 413 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 67 (26 residues), see Phobius details amino acids 79 to 101 (23 residues), see Phobius details amino acids 143 to 161 (19 residues), see Phobius details amino acids 184 to 202 (19 residues), see Phobius details amino acids 215 to 237 (23 residues), see Phobius details amino acids 250 to 269 (20 residues), see Phobius details amino acids 289 to 314 (26 residues), see Phobius details amino acids 322 to 340 (19 residues), see Phobius details amino acids 346 to 367 (22 residues), see Phobius details signal peptide" amino acids 31 to 31 (1 residues), see Phobius details PF00375: SDF" amino acids 12 to 393 (382 residues), 431.2 bits, see alignment E=1.9e-133

Best Hits

Swiss-Prot: 40% identical to GLT_PYRHO: Glutamate transporter homolog (PH1295) from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)

KEGG orthology group: None (inferred from 100% identity to son:SO_3562)

MetaCyc: 33% identical to C4 dicarboxylate/orotate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-121; TRANS-RXN-121A; TRANS-RXN-121C; TRANS-RXN-122A; TRANS-RXN0-451; TRANS-RXN0-517; TRANS-RXN0-553

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EBF6 at UniProt or InterPro

Protein Sequence (413 amino acids)

>SO3562 proton/glutamate symporter, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MILQTISRIPFWQKVLTGFILGALVGVLLGESATVLKPLGDLFISAIKMLVAPLVFCSIV
VSITSLGSQTNLKRLSIKTLGMFMLTGTIASLIGLAVGSLIDMGGTMQLATTEVRERNIP
GFAQVLLDMIPINPFASLAEGKVLQIIVFAALVGIAINKVGEKAEPLKRTIEAGAEVMFQ
LTRMVLKLTPIGVFGLMAWVVGEYGLSTLLPLGKFIAAIYIAALVHMIFVYGGFVKLAGL
SPIQFFRKALPAQLVAFSTSSSFGTLPASTRAVETMGVSKRYSAFVMPLGATMNMDGCGG
IYPAIAAIFIAQIYGIPLDTLDYVMIAVTATIASVGTAGVPGSAMVMLTVTLGVIGLPLE
GIAFIASIDRIIDMIRTTTNVTGDMMTAVVIGKSENELDVEQFNAKDTQASLA