Protein Info for SO3534 in Shewanella oneidensis MR-1

Name: mviN
Annotation: MviN protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 519 transmembrane" amino acids 9 to 23 (15 residues), see Phobius details amino acids 28 to 46 (19 residues), see Phobius details amino acids 93 to 121 (29 residues), see Phobius details amino acids 137 to 159 (23 residues), see Phobius details amino acids 167 to 188 (22 residues), see Phobius details amino acids 198 to 218 (21 residues), see Phobius details amino acids 246 to 275 (30 residues), see Phobius details amino acids 282 to 301 (20 residues), see Phobius details amino acids 322 to 346 (25 residues), see Phobius details amino acids 359 to 380 (22 residues), see Phobius details amino acids 392 to 412 (21 residues), see Phobius details amino acids 418 to 438 (21 residues), see Phobius details amino acids 450 to 471 (22 residues), see Phobius details amino acids 489 to 510 (22 residues), see Phobius details TIGR01695: murein biosynthesis integral membrane protein MurJ" amino acids 4 to 511 (508 residues), 464 bits, see alignment E=3.2e-143 PF03023: MurJ" amino acids 30 to 478 (449 residues), 489 bits, see alignment E=1.2e-150 PF14667: Polysacc_synt_C" amino acids 369 to 509 (141 residues), 50.5 bits, see alignment E=2.6e-17

Best Hits

Swiss-Prot: 70% identical to MURJ_VIBCH: Probable lipid II flippase MurJ (murJ) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03980, virulence factor (inferred from 100% identity to son:SO_3534)

Predicted SEED Role

"Proposed peptidoglycan lipid II flippase MurJ" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EBI2 at UniProt or InterPro

Protein Sequence (519 amino acids)

>SO3534 MviN protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MSKKLLKSGMIVSAMTLISRVLGLVRDVVVANLLGAGTSADVFFFANKIPNFLRRLFAEG
AFAQAFVPVLTEYQEKHTSDETRELLSKVAGTLGLLVTVVTLVGVIASPVLSALFGGGWF
VAWLNNEPDGAKFELATVVLKITFPYLWFITFTALAGSILNTRGRFAVSAFTPVFLNVAI
IAAAMFFAPTSSQPEITLAWGVFWGGLIQFLFQIPFLLREKALVKPSWGWNHPGVVKIRT
LMIPALFGVSVSQINLLFDTFIASFLMTGSISWLYYSDRLLEFPLGLFGIAIATVILPAL
SRNHVNAEGDGFGKTMDWGIKAILLLGLPAMMGLIVLAQPMLMVLFMRGAFTINDVQMAS
YSLMAYGSGLLSFMLIKVLAPGYYSRQDTKTPVRYGIIAMITNMVFNLIFAIPFGYVGLA
VATSMSALLNATLLYRGLHKAGVYRITKPTMVFFLKAVVSTALMVVVLYYLLPSQSQWLE
WGLALRAKALIGLIVVGAMTYLVGLLALGIRPWSMKRGV