Protein Info for SO3507 in Shewanella oneidensis MR-1

Updated annotation (from data): N-acetylglucosamine kinase (EC 2.7.1.59)
Rationale: Specifically important for: N-Acetyl-D-Glucosamine. First step in NAG catabolism; (SEED_correct); see PMID 16857666
Original annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01869: BcrAD_BadFG
  • amino acids 13 to 274 (262 residues), 107.1 bits, E=6.2e-35

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_3507)

Predicted SEED Role

"N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59)" in subsystem Chitin and N-acetylglucosamine utilization (EC 2.7.1.59)

MetaCyc Pathways

• N-acetylglucosamine degradation II (3/3 steps found)
• chitin derivatives degradation (3/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.59

Sequence Analysis Tools

See Q8EBK6 at UniProt or InterPro

Protein Sequence (300 amino acids)

>SO3507 N-acetylglucosamine kinase (EC 2.7.1.59) (Shewanella oneidensis MR-1)
MGLVQTNDQQLFIGVDGGGSKCRATIYTADGTVLGTGVAGRANPLHGLAQTFESIEASAH
QALLDAGMKATDSHLLVAGLGLAGVNVPRLYQDVVNWQHPFAAMYVTTDLHTACIGAHRG
ADGAVIITGTGSCGYAHVGDASLSIGGHGFALGDKGSGAWLGLKAAEHVLLALDGFATPT
ALTEMLLSHLGVKDALGIVEHLAGKSSSCYAQLARNVLDCANAGDQVAIAIVQEGADYIS
EMARKLFMLNPVRFSMIGGLAEPLQAWLGSDVVAKISETLAPPELGAMYYAQQQFNSATV