Protein Info for SO3251 in Shewanella oneidensis MR-1

Name: cheR-2
Annotation: chemotaxis protein methyltransferase CheR (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 PF03705: CheR_N" amino acids 11 to 54 (44 residues), 44.6 bits, see alignment 1.8e-15 PF01739: CheR" amino acids 78 to 270 (193 residues), 196.3 bits, see alignment E=7.4e-62

Best Hits

Swiss-Prot: 63% identical to CHER1_VIBCH: Chemotaxis protein methyltransferase 1 (cheR1) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K00575, chemotaxis protein methyltransferase CheR [EC: 2.1.1.80] (inferred from 98% identity to shw:Sputw3181_1405)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EC93 at UniProt or InterPro

Protein Sequence (279 amino acids)

>SO3251 chemotaxis protein methyltransferase CheR (NCBI ptt file) (Shewanella oneidensis MR-1)
MNVPDKSLAEAEYNQFRLFLEQHSGIVLGENKQYLVRSRLAPLMGKYNLPSLSDVVKHSM
KPTERALRAEVIDAMTTNETLWFRDRYPFELLNNVLLPEYSKLGRPLKIWSAACSSGQEP
YSLAMTILEYQQKKPGALSGGASIQATDLSPSMLERCKNAEYDSLALARGLSDERKRQFF
DALPSGNMRIKDNVKRLVNFRAHNLLESYTLLGKFDIIFCRNVLIYFAPEAKAKILRQFA
AALNPKGILFLGASESIAGLTDEFDMVRCNPGIYYQKKT