Protein Info for SO3102 in Shewanella oneidensis MR-1

Annotation: AcrA/AcrE family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 26 to 327 (302 residues), 178.7 bits, see alignment E=7.1e-57 PF16576: HlyD_D23" amino acids 48 to 261 (214 residues), 61.8 bits, see alignment E=1.1e-20 PF13533: Biotin_lipoyl_2" amino acids 50 to 96 (47 residues), 26.2 bits, see alignment 1e-09 PF13437: HlyD_3" amino acids 159 to 258 (100 residues), 40.7 bits, see alignment E=6.8e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_3102)

Predicted SEED Role

"Membrane-fusion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ECN4 at UniProt or InterPro

Protein Sequence (337 amino acids)

>SO3102 AcrA/AcrE family protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MTAISRTLFTLLAFSTLTTQAASLETLEVMSKPHANWLTLDASIEAVKAATVSAQTSGRI
VKLNYDVNDVVPEGAALLEITSKEQGAELASYEADLAKATALNVEAQAQFKRYTELFPQG
AISKGAMDEATANAKAAEQAVSAAKARVIKATESLKYTVVSAPFSGIVTERLVELGETVS
VGQPLLSGFSPSQMRAITQVPQRYIPQLKNAPEFIVRLNDGRELTSQDLTIFSFADPVTH
SYQVRINLPKDEANLQPGTWVKALFKNGEREKIQLPTSALITMNELSSVYLKKGDQFVLT
QVRVTEPLDGEVEVLAGLKSGDIVAMDAYQVLLEQKQ