Protein Info for SO3073 in Shewanella oneidensis MR-1

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 643 TIGR03197: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain" amino acids 223 to 640 (418 residues), 529.5 bits, see alignment E=3e-163 PF01266: DAO" amino acids 223 to 610 (388 residues), 157.3 bits, see alignment E=8.3e-50

Best Hits

Swiss-Prot: 100% identical to MNMC_SHEON: tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC (mnmC) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: None (inferred from 100% identity to son:SO_3073)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ECR0 at UniProt or InterPro

Protein Sequence (643 amino acids)

>SO3073 conserved hypothetical protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MMGQWGLGDGIELLSFIHYWQTLAKTQNLPRLLLKVFEPNPINYYELKLLWDQSQSLILH
PHLQPIANAIIEAKPARIIGCQRLIFDDGRISLDLDFGDLQTMLVNQPHCGTYPIQQWLI
LPHLAPQLSRKILWQMARLSADDAHFIGVELAETTQNLAKTCGFSPLTITADMLCGEQID
SIASQIVTDDILLHERKLLRQQANNHQAFTPRPSQVASTKQPIAIIGGGLASAHLMLSLA
EREQSSILFCKDNDLGQGASGNRQGAIYPLLTPENDELSRFFQQAFLFSRRRIAALSLAS
MKGSDVASGVMPISHDFCGVLQTGHDERSQQRLDKIIQSQDWPAEIAYAVDASEANKIAK
IGIDKAGFYYPLGGWVCPFEYAKAAVDKASQLANVQCHFNTEITEIERDAKGWYLLSQDQ
RFGPFRQLVLANGAQLTQFSASERLQISPFRGQVSHIPSQFQLSQLATVLCANGYLTPSH
QGLHCLGASYVKAAEHLDFCPLEQLENLGKMQQSYPNQDWVEDIDISANSARVGVRMVTR
DHFPMMGCAPDVNEIWARYEQHQINQQQAEQIRHYWQTTPAPIHDGLYILGGLGSRGLSS
GPLAAECLAAQLTDEPLPLDWPTLNKLSPNRMWLRKLLKGKAL