Protein Info for SO2884 in Shewanella oneidensis MR-1
Updated annotation (from data): ycgB component of nitrogen-related signalling system (of yeaGH-ycgB)
Rationale: conserved cofitness; yeaG is a protein kinase
Original annotation: conserved hypothetical protein (NCBI ptt file)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 71% identical to YCGB_ECOLI: Uncharacterized protein YcgB (ycgB) from Escherichia coli (strain K12)
KEGG orthology group: None (inferred from 100% identity to son:SO_2884)Predicted SEED Role
"FIG004684: SpoVR-like protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q8ED81 at UniProt or InterPro
Protein Sequence (508 amino acids)
>SO2884 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (Shewanella oneidensis MR-1) MGMKESKTRIALSDGPDWSFELLQSYLKEIERVAAIYKLNAYPNQIEIITAEQMMDAYAG IGMPIGYTHWSFGKRFIETEQGYKRGQMGLAYEIVINSNPCIAYLMEENTITMQALVMAH ACFGHNSFFKNNYLFKTWTDASSIIDYLVFAKNYISDCEQKYGIEQVESVIDSCHALMNY GVDRYKRPAEISFREEQARQKDREAYLQSQVNDLWRTIPTHQQQQPSTTKRRFPAEPQEN ILYFIEKNAPLLEPWQREIIRIVRKMAQYFYPQKQTQVMNEGWATFWHYTILNHLYDDGV VSDRFMMEFLQSHTGVVAQPEYNSRYYSGINPYALGFAMFTDIRRICEAPTDEDRIWFPD IAGSNWLDTLHFAMQNFKDESFISQYLSPRVIRQFKLFGIHDDEKRNYLSVSAIHDEQGY QDIRNLLSQQYNLSNIEPNIQVHNVEINGDRSLTLRYVPNKDIPLAGSYNEVLKHLHRLW GFSVSLEQVNADNSVTLLSKCPEQPKAD