Protein Info for SO2880 in Shewanella oneidensis MR-1

Annotation: glutaredoxin domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 110 TIGR00365: monothiol glutaredoxin, Grx4 family" amino acids 4 to 100 (97 residues), 149.5 bits, see alignment E=1.3e-48 PF00462: Glutaredoxin" amino acids 16 to 80 (65 residues), 69.1 bits, see alignment E=1.6e-23

Best Hits

Swiss-Prot: 75% identical to GLRX4_ECOL6: Glutaredoxin 4 (grxD) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K07390, monothiol glutaredoxin (inferred from 100% identity to son:SO_2880)

Predicted SEED Role

"Glutaredoxin-related protein" in subsystem Glutaredoxins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ED84 at UniProt or InterPro

Protein Sequence (110 amino acids)

>SO2880 glutaredoxin domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
METVEKIKQQIGENPIIVYMKGSPKLPSCGFSCQVAQIMINCGEQFAFVDILQHPDIRAE
LPKYANWPTFPQLWIEGELIGGCDIVVDMYQKGELQPLIKATAEKYKTAE