Protein Info for SO2866 in Shewanella oneidensis MR-1

Name: iciA
Annotation: chromosome initiation inhibitor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 TIGR03298: transcriptional regulator, ArgP family" amino acids 2 to 302 (301 residues), 356.5 bits, see alignment E=4.8e-111 PF00126: HTH_1" amino acids 6 to 61 (56 residues), 62 bits, see alignment E=4.3e-21 PF03466: LysR_substrate" amino acids 92 to 277 (186 residues), 29 bits, see alignment E=6.9e-11

Best Hits

KEGG orthology group: K05596, LysR family transcriptional regulator, chromosome initiation inhibitor (inferred from 100% identity to son:SO_2866)

Predicted SEED Role

"Chromosome initiation inhibitor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ED96 at UniProt or InterPro

Protein Sequence (306 amino acids)

>SO2866 chromosome initiation inhibitor (NCBI ptt file) (Shewanella oneidensis MR-1)
MLEYANLKALAVVVSEGGFERAAKVLHITQSAVSQRVRQLEERVGQSLLIRSTPVVATPT
GKRLLRHYSQVQLLESELRSELDADDPNHPTTVRIAVNADSLATWFLPALADMFSRHAWL
LELIVDDESYTHHLLKNGEAVGCVTTTANPMAGCSSEFLGTMEYMCVATPQFAARYFEWS
DTSNDSGSQLTQAQLTKAPAVVFSTKDKLHEKYLAQYFQMTPGRWWQHTIPSSESFLEAI
NLSLGYGLVGHLQAKPLIDQGVLIELTPEKRMRVPLYWQHWNIKAKQTTLVYRALAATAQ
HHLLQQ