Protein Info for SO2768 in Shewanella oneidensis MR-1

Annotation: acyl-CoA dehydrogenase family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 596 transmembrane" amino acids 514 to 536 (23 residues), see Phobius details PF12418: AcylCoA_DH_N" amino acids 4 to 34 (31 residues), 35.4 bits, see alignment (E = 2.2e-12) PF02771: Acyl-CoA_dh_N" amino acids 80 to 157 (78 residues), 43.6 bits, see alignment E=8.8e-15 PF02770: Acyl-CoA_dh_M" amino acids 162 to 271 (110 residues), 43.5 bits, see alignment E=7.2e-15 PF00441: Acyl-CoA_dh_1" amino acids 282 to 450 (169 residues), 63.1 bits, see alignment E=8.8e-21 PF12806: Acyl-CoA_dh_C" amino acids 470 to 591 (122 residues), 100.8 bits, see alignment E=1.6e-32

Best Hits

KEGG orthology group: K00257, [EC: 1.3.99.-] (inferred from 100% identity to son:SO_2768)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7, 1.3.99.-

Use Curated BLAST to search for 1.3.8.7 or 1.3.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EDI1 at UniProt or InterPro

Protein Sequence (596 amino acids)

>SO2768 acyl-CoA dehydrogenase family protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MPVYQAPLRDYQFILDEMLHIYQQDALKGFDEIDPELVDAILQGMADFSTEVMLPLNSIG
DVQGCKLVEGNVVTPEGFADAYQQFVDNGWPTLTCDPAFGGQGLPEVVGIFVTEMQTSTN
MAFAMYPGLTHGAYSAIHAHGSEALKQKYLPKLVSGEWTGTMNLTESHAGTDLALLRTKA
VPAADGYFAITGEKIFISSGDHPFTDNIVHLVLARLPDAPEGVKGISLFAVPKVLVNSDG
SLGQANSLYASGLEHKMGIHGNSTCVMVFDGALGELVGEPHQGLRAMFTMMNQARLGVGM
QGLGVSEIAYQNALAYAKDRLQSRAISGAKAPEKAADPILVHGDVRRMLLSQKAFNEGAR
ALVGQQALWLDEAERHSDPAKAKAASQLAALFTPVVKGFITNRGFNACVDAQQVFGGHGY
IHEWGMEQFVRDSRIALIYEGTNGIQALDLVGRKLLSDRGAAMQQWSTLVTEFIQSQGKD
AQMQPYVSGLMDCATDLQKASGYLATHAASNPDIIGAASMAYLELFGITALAWMWARMAN
IALTALDNGTEEVGFYQAKLKTADFYMAYWAVQSRSLRKQLEQASEMLTQLDETIF