Protein Info for SO2752 in Shewanella oneidensis MR-1

Annotation: conserved hypothetical protein TIGR00051 (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 133 TIGR02799: tol-pal system-associated acyl-CoA thioesterase" amino acids 3 to 127 (125 residues), 163 bits, see alignment E=3.8e-52 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family" amino acids 7 to 122 (116 residues), 108.9 bits, see alignment E=1.9e-35 PF13279: 4HBT_2" amino acids 12 to 122 (111 residues), 60.8 bits, see alignment E=1.8e-20 PF03061: 4HBT" amino acids 17 to 95 (79 residues), 56.5 bits, see alignment E=2.8e-19

Best Hits

Swiss-Prot: 48% identical to YBGC_ECO57: Acyl-CoA thioester hydrolase YbgC (ybgC) from Escherichia coli O157:H7

KEGG orthology group: K07107, acyl-CoA thioester hydrolase [EC: 3.1.2.-] (inferred from 96% identity to spc:Sputcn32_1603)

Predicted SEED Role

"4-hydroxybenzoyl-CoA thioesterase family active site" in subsystem Ton and Tol transport systems

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.2.-

Use Curated BLAST to search for 3.1.2.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EDJ4 at UniProt or InterPro

Protein Sequence (133 amino acids)

>SO2752 conserved hypothetical protein TIGR00051 (NCBI ptt file) (Shewanella oneidensis MR-1)
MTFNWPISVYYEDTDAGGVVYHSNYLNFFERARTEWLKALGVSQTALLADDTAFVVKRAE
LDFKKAARFEQNLIVETKVIELKKASLVFHQRLVDHLGDCYCEGTVLVACVALSRMRPRA
IPLNIVQEFDSAS