Protein Info for SO2612 in Shewanella oneidensis MR-1

Name: holB
Annotation: DNA polymerase III, delta prime subunit (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00678: DNA polymerase III, delta' subunit
  • amino acids 20 to 203 (184 residues), 211 bits, E=5.8e-67
• PF13177: DNA_pol3_delta2
  • amino acids 21 to 170 (150 residues), 141.1 bits, E=1.7e-45

Best Hits

KEGG orthology group: K02341, DNA polymerase III subunit delta' [EC: 2.7.7.7] (inferred from 100% identity to son:SO_2612)

Predicted SEED Role

"DNA polymerase III delta prime subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

• Purine metabolism
• Pyrimidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

See Q8EDX9 at UniProt or InterPro

Protein Sequence (318 amino acids)

>SO2612 DNA polymerase III, delta prime subunit (NCBI ptt file) (Shewanella oneidensis MR-1)
MVEHRGFDVLSLPWLDVPRQAFLTQLQTQKVPHAQLVGIDSAYGGELLSVFMARAAMCSQ
PTHTGGCGFCKSCQLFDAGNHPDFYQIEADGHQIKVDQIRELCSRLSATAQQSGRRVAII
HHSERLNSASANALLKTLEEPGKDTLLLLHSDTPARLMATISSRCQRLPFVAPSKTLIKN
WLIQQCQIQEDVTWCLSVVGGPLKLAESLQSNSTQPSRYQTLLGFRKDWAQSLSSGHLCA
SLLIISEQQIIDALKVLYLLLRQILLKNGNQDAYVQAQIGNLAAKVMGMCHSLSAMPSVN
YLGLCQSYVLEYRDITNK