Protein Info for SO2610 in Shewanella oneidensis MR-1

Annotation: hydrolase, TatD family (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 TIGR00010: hydrolase, TatD family" amino acids 2 to 254 (253 residues), 295.9 bits, see alignment E=1.2e-92 PF01026: TatD_DNase" amino acids 3 to 254 (252 residues), 278.6 bits, see alignment E=2.4e-87

Best Hits

Swiss-Prot: 57% identical to YCFH_ECOL6: Uncharacterized metal-dependent hydrolase YcfH (ycfH) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K03424, TatD DNase family protein [EC: 3.1.21.-] (inferred from 100% identity to son:SO_2610)

Predicted SEED Role

"Putative deoxyribonuclease YcfH" in subsystem YcfH

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.-

Use Curated BLAST to search for 3.1.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EDY1 at UniProt or InterPro

Protein Sequence (262 amino acids)

>SO2610 hydrolase, TatD family (NCBI ptt file) (Shewanella oneidensis MR-1)
MLIDSHCHLDRLKAAPDQPTLELILANAKARGVDYMLCVNVRQQGFESMRDKVAGFEQVF
LSSGVHPLDVKEGLDVEQIRRFAMEPKVVAIGETGLDYFYADETKSLQQQCFEQQIALAV
EVNKPLIVHTRDAREDTINMLKTGQAEKVGGVLHCFTENWEMAKAAIDLGFYISVSGIVT
FKNAGELRTVIRKVPKERLLVETDSPYLAPIPHRGQENQPAYVRDVAEFVAELRGERYED
LAQYTSENFFNLFKDAARLIGR