Protein Info for SO2498 in Shewanella oneidensis MR-1

Annotation: sensory box protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 775 PF01590: GAF" amino acids 73 to 212 (140 residues), 39.4 bits, see alignment E=2.1e-13 TIGR00229: PAS domain S-box protein" amino acids 221 to 335 (115 residues), 36.9 bits, see alignment E=3.6e-13 PF13426: PAS_9" amino acids 238 to 329 (92 residues), 41.6 bits, see alignment E=3.2e-14 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 346 to 502 (157 residues), 63 bits, see alignment E=2.8e-21 PF00990: GGDEF" amino acids 354 to 497 (144 residues), 67.9 bits, see alignment E=2.3e-22 PF00563: EAL" amino acids 520 to 753 (234 residues), 233.3 bits, see alignment E=6.5e-73

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_2498)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EE90 at UniProt or InterPro

Protein Sequence (775 amino acids)

>SO2498 sensory box protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MADVAVLNIDSVICVNKNNDKSTPLTQLFLVLVAAESFYPTRRFVGIRVKRRQHQHLLES
LVHSTAKQQGDFTKTAELATELLCQNLAVSLVSIWIFSADQGTQSLVAQFGSMALQDTYR
PSLLHTVPRYLNELKNYRHIDAGNTLIDPRLTELVDSYFIPRQILSSLDVGIRINGHLEG
VLCIERAQVTHHWHDSEIHLACQMADQLALTLATKHAYDKEERLSLFRCAIEQSRQMSML
INLHTEKVEYVNQAHEDITGIARDKSIGTNLRDLTFFRQHNALAEQTLAKIFRGDQAKGE
VQFSRTDGSRYWLKYIVSQFITDRGNHYALVSGEENSDEHNYKAELERLAWRCGLTGLNN
RSHFNRVLERTTHGLLLLVDLVAFKRFNDTYGHENGDSLLIEVGRRLKHFSEINKATEIA
RVGSDEFAVLLTDDNAVYDLDYFSTRLYQHLAMPILIGREQVEPKPALAVVDIASVANLF
APLTCADIAVQYAKKKKGTAIQVFNSTLLSAFKEDAQIERDLHSAIRGRQFELYYQPLRD
LEQQTYIGAEALIRWHHPKKGVLYPGAFIDIAEQSGMINAIGSWVLEAACRQLNIWQHHN
ADLSMHVNVSARQFFSGNLYEQVWQLLTRYRLKPKTLILEITETELMGDIRHATLLCQEL
AELGVGLAIDDFGTGYSSMRYLKQFPISKLKIDRSFISDLTISRESQEIVSAIIAMANAL
NISLTAEGVETAEQEAFLAKSLCHQAQGFLYSPALREPEFAQFLLTAKQPNLIAH