Protein Info for SO2494 in Shewanella oneidensis MR-1

Annotation: zinc-dependent metallopeptidase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 619 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF01401: Peptidase_M2" amino acids 45 to 619 (575 residues), 814.6 bits, see alignment E=2.7e-249

Best Hits

KEGG orthology group: K01283, peptidyl-dipeptidase A [EC: 3.4.15.1] (inferred from 100% identity to son:SO_2494)

Predicted SEED Role

"Peptidyl-dipeptidase A precursor (EC 3.4.15.1)" (EC 3.4.15.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.15.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EE93 at UniProt or InterPro

Protein Sequence (619 amino acids)

>SO2494 zinc-dependent metallopeptidase (NCBI ptt file) (Shewanella oneidensis MR-1)
MAILLNRPTTLALTIALTLNLTACNNKQNTSETKTSIPASTSTPDKAQAIAFIQDAEAQM
AQLSIEANRAEWIYSNFITEDTAALSAAVGEKVSAASVKFATEAAKYANVELDPANARKL
NILRSALVLPAPLDPAKNAELAQISSELNGLYGKGKYCFADGKCMTQPELSSLMAESRDP
AKLLEAWKGWREIAKPMRPLFQREVELANEGAKDLGYANLSELWRSQYDMKPDEFSQELD
RLWSQVKPLYESLHCYVRGELNKEYGDAIAPKTGPIPAHLLGNMWAQQWGNVYDLVAPEN
ADPGYDVTELLAQKGYDEHRMVKQAESFFTSLGFAPLPDSFWSRSLFLQPKDRDVVCHAS
AWDLDNLDDIRIKMCIQKTAEDFTVIHHELGHNFYQRAYKQQPFLFKNSANDGFHEAIGD
TIALSITPSYLKQIGLLEEVPDASKDIGLLLKQALDKIAFLPFGLMIDQWRWKVFSGEIT
PAQYNQAWWELREKYQGVKAPTPRSETDFDPGAKYHVPGNVPYTRYFLAHILQFQFHKAL
CETAGDKGPVHRCSIYGNQAAGEKLNRMLELGSSQPWPMALKEVTGTETMDANAVLDYFA
PLKTWLDEQNKAANRQCGW