Protein Info for SO2474 in Shewanella oneidensis MR-1

Annotation: carbonic anhydrase family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00484: Pro_CA
  • amino acids 37 to 187 (151 residues), 187.2 bits, E=1.2e-59

Best Hits

Swiss-Prot: 58% identical to CAN_ECOLI: Carbonic anhydrase 2 (can) from Escherichia coli (strain K12)

KEGG orthology group: K01673, carbonic anhydrase [EC: 4.2.1.1] (inferred from 100% identity to son:SO_2474)

MetaCyc: 58% identical to carbonic anhydrase 2 (Escherichia coli K-12 substr. MG1655)
Carbonate dehydratase. [EC: 4.2.1.1]

Predicted SEED Role

"Carbonic anhydrase (EC 4.2.1.1)" in subsystem Carboxysome or Cyanate hydrolysis (EC 4.2.1.1)

MetaCyc Pathways

• CO₂ fixation into oxaloacetate (anaplerotic) (2/2 steps found)
• C4 photosynthetic carbon assimilation cycle, NAD-ME type (8/11 steps found)
• cyanate degradation (2/3 steps found)
• C4 photosynthetic carbon assimilation cycle, NADP-ME type (4/7 steps found)
• C4 photosynthetic carbon assimilation cycle, PEPCK type (9/14 steps found)
• gluconeogenesis II (Methanobacterium thermoautotrophicum) (8/18 steps found)
• 3-hydroxypropanoate cycle (4/13 steps found)
• 3-hydroxypropanoate/4-hydroxybutanate cycle (7/18 steps found)
• glyoxylate assimilation (3/13 steps found)
• superpathway of the 3-hydroxypropanoate cycle (4/18 steps found)
• Methanobacterium thermoautotrophicum biosynthetic metabolism (22/56 steps found)

KEGG Metabolic Maps

• Nitrogen metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.1

Sequence Analysis Tools

See Q8EEB3 at UniProt or InterPro

Protein Sequence (201 amino acids)

>SO2474 carbonic anhydrase family protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MKLLKPLFDNNLRWAGRISQEHPDFFEQLAKQQNPEYLWIGCSDSRVPSNQIIDLMPGEV
FVHRNIANMVIHTDLNCLSVLQYAIDVLKVKHIMVVGHYGCGGVRAAMGNQRLGLIDNWL
GHLRDVYRLHHDELMQMDEAKRFDRLCELNVIEQVSNVTSSTIVQEAWARGQELAVHGWI
YGIDNGLLTDLDVTVDRAQVV