Protein Info for SO2450 in Shewanella oneidensis MR-1

Name: susB
Annotation: alpha-glucosidase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 699 signal peptide" amino acids 1 to 43 (43 residues), see Phobius details PF14508: GH97_N" amino acids 47 to 296 (250 residues), 237.2 bits, see alignment E=2.7e-74 PF10566: Glyco_hydro_97" amino acids 314 to 501 (188 residues), 219 bits, see alignment E=5.2e-69 PF14509: GH97_C" amino acids 596 to 697 (102 residues), 109.7 bits, see alignment E=1.1e-35

Best Hits

KEGG orthology group: K01187, alpha-glucosidase [EC: 3.2.1.20] (inferred from 100% identity to son:SO_2450)

Predicted SEED Role

"Alpha-glucosidase (EC 3.2.1.20)" in subsystem D-Galacturonate and D-Glucuronate Utilization or Maltose and Maltodextrin Utilization (EC 3.2.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.20

Use Curated BLAST to search for 3.2.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EED2 at UniProt or InterPro

Protein Sequence (699 amino acids)

>SO2450 alpha-glucosidase (NCBI ptt file) (Shewanella oneidensis MR-1)
MFIKANAIQLTTLQSNLRSQRRLSPMCIALTVSSFFSANLVAQTVTLSSPNQHIQISLSD
DTGRAEYKIDFHGKTIIEPSRLGLVFQSIGELGQGLRIKSSHITSTDDKWQQPWGEQEWI
KDQHNQLSVVLTDGKIDLNLEFNAFDDGIGFRYHLAEQAALPVDTPLSITDELTEFNIGQ
SNKATAWWIPSRGWNRYEYLYRTSALNQVDRAHTPFTFRLADGTHLSIHEAALVNFASMT
LDQQRDGKLKADLTPWSDGIRVKTQAGFYTPWRTIQIADKATGLLNSHLILNLNEPNKLG
DVSWIKPGKYVGIWWGMHLNKNTWGSGPKHGATTSETKRYMDFAAKYHFDGVLVEGWNQG
WDGDWFHNGDQFSFTKAYDDFDLPAITAYGAKKGVRLIGHHETAGSVTHYRKQMADAFIL
YEKHGVTQVKTGYVADGGQIKRFDENGIMRHEWHDGQFMVGEYLYNVTEAAKHHISINTH
EPIKDTGLRRTYPNWISREGARGQEYNAWGSPPNSPEHTAMLPFTRMLAGPMDFTPGIFD
LAPKGLDAENRVQTTLMKQLALYVVLYSPIQMAADLPRNYQKHLDAFQFIRDVPTDWYQS
IALAGEVGDYVVFARQAKDQKDWYLGALTDETARKVTVKLDFLDPHKRYQAQIYRDGAKA
DWKTNPYDYVIETKEVSAKDSLNLALASSSGTAIRFKVL