Protein Info for SO2290 in Shewanella oneidensis MR-1

Annotation: rhodanese domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 PF17773: UPF0176_N" amino acids 5 to 95 (91 residues), 95.2 bits, see alignment E=2.5e-31 PF00581: Rhodanese" amino acids 116 to 210 (95 residues), 45.5 bits, see alignment E=9e-16

Best Hits

Swiss-Prot: 100% identical to Y2290_SHEON: UPF0176 protein SO_2290 (SO_2290) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K07146, UPF0176 protein (inferred from 100% identity to son:SO_2290)

Predicted SEED Role

"Rhodanese domain protein UPF0176"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EES8 at UniProt or InterPro

Protein Sequence (333 amino acids)

>SO2290 rhodanese domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MSNVVVCALYKFVSLPHFESLREPLLSMMEQAEIKGTLLLASEGINGTVAGNQAAIDALL
IWLNQQNGLENITYKLSFDDEMPFYRTKVKLKKEIVTMGVEGIDPLKVVGTYVKPKDWNA
LISDPEVVLVDTRNDYEVQIGTFKNAINPVTETFREFPEYVKQNLDPAKHKKVAMFCTGG
IRCEKSTAYLKEQGFEEVYHLEGGILKYLEEVNKAESLWEGECFVFDNRVAVDHDLKKGQ
YDQCNACRMPITEAEKLTPDYVQGVSCPHCIDKISEEQRKRFVERERQVNLAKSRNEAHI
GSDVNHVIEARRQKKEALRKQSAEKNKAKQANA