Protein Info for SO2203 in Shewanella oneidensis MR-1

Name: dgkA
Annotation: diacylglycerol kinase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01219: DAGK_prokar
  • amino acids 29 to 129 (101 residues), 120.3 bits, E=1.4e-39

Best Hits

Swiss-Prot: 52% identical to KDGL_ECO57: Diacylglycerol kinase (dgkA) from Escherichia coli O157:H7

KEGG orthology group: K00901, diacylglycerol kinase [EC: 2.7.1.107] (inferred from 100% identity to son:SO_2203)

MetaCyc: 52% identical to diacylglycerol kinase (Escherichia coli K-12 substr. MG1655)
Diacylglycerol kinase. [EC: 2.7.1.107]

Predicted SEED Role

"Diacylglycerol kinase (EC 2.7.1.107)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.1.107)

MetaCyc Pathways

• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• phosphatidate metabolism, as a signaling molecule (1/5 steps found)
• type I lipoteichoic acid biosynthesis (S. aureus) (5/17 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism
• Phosphatidylinositol signaling system

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.107

Sequence Analysis Tools

See Q8EF02 at UniProt or InterPro

Protein Sequence (134 amino acids)

>SO2203 diacylglycerol kinase (NCBI ptt file) (Shewanella oneidensis MR-1)
MRTIAQVDGIIMKPANNHGIKRIFRATGFSMKGLKAAWIHEAAFRQELMLAVVMLPVAFL
VDISTMERLMLILTLFIVLIVELLNSAIEAVVDRVGSEIHHLSGQAKDIASAAVFMSLAL
CGITWLVVLLPLLV