Protein Info for SO2192 in Shewanella oneidensis MR-1

Annotation: sensor histidine kinase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 687 transmembrane" amino acids 390 to 411 (22 residues), see Phobius details TIGR03785: proteobacterial dedicated sortase system histidine kinase" amino acids 1 to 685 (685 residues), 1092.4 bits, see alignment E=0 PF00512: HisKA" amino acids 468 to 530 (63 residues), 42.2 bits, see alignment E=7e-15 PF02518: HATPase_c" amino acids 577 to 686 (110 residues), 51.7 bits, see alignment E=1.1e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_2192)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EF13 at UniProt or InterPro

Protein Sequence (687 amino acids)

>SO2192 sensor histidine kinase (NCBI ptt file) (Shewanella oneidensis MR-1)
MEKYLRHGQERTLEGTTQALATALHERPKLFDGQASFLKQVEKSRDLYAYPLAGAILLDG
KLNEWQEYQHRFIQYGEANQIMRADPSAPLTLSFTHMVGQYDGYLYAFFQVVDPNVVFRG
KNALSVDRNDHLSIATLAPDNKFKRYIVATTQPGWISAFELPANPKQTVPVTPEVRIQGQ
WATTDVGYNIELRIPLDMVGSKLGFAIADVNDSKYRDVAAVVGTSALDTVDKLGTVLVPS
PEIENIIKGMSHYSSRIWVIDKHGRVLAKSGDIRDSNSVWTRTLDDENSNGLWQRFQRDY
LHPLYYKILTKPPKDFIDSLRDSTELNGSHIQKALAGQQTSTWRLTPDNKAVVLAAASPI
WIDNNVMGAVVAEETTHGIRTLRNRALEKLFNVILTIMSMGTLALFFFASSISNRIRKLR
DEAENAIDSQGRVRNHLKPSKARDEIGDLSRSFASIVGRLGQYTHYLENMSSRLSHELRT
PVAVVRSSLEHLNLQTLDKDTQKYVDRAQEGVSRLSMILNNMSEATRLEQSLTQADVTKF
PLSQVVSGCMQGYQMTYPEQRFSIKVPDQPLMMQGVPEYIAQLMDKLIANAIEFCHQGSS
IEVTLTQVGKQATLLISNLGPQLPVDMSEQIFDSMVSVRDNQTQEKPHLGLGLYIARLVT
EFHQGNILARNRSENDGVDILVTLPLC