Protein Info for SO2147 in Shewanella oneidensis MR-1

Name: recD
Annotation: exodeoxyribonuclease V, alpha subunit (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 712 TIGR01447: exodeoxyribonuclease V, alpha subunit" amino acids 27 to 698 (672 residues), 545.2 bits, see alignment E=1e-167 PF21185: RecD_N" amino acids 33 to 132 (100 residues), 63.3 bits, see alignment E=9.9e-21 PF13245: AAA_19" amino acids 195 to 357 (163 residues), 121.5 bits, see alignment E=1.2e-38 PF13604: AAA_30" amino acids 196 to 384 (189 residues), 88.4 bits, see alignment E=2.2e-28 PF00580: UvrD-helicase" amino acids 200 to 264 (65 residues), 24.1 bits, see alignment E=1.1e-08 PF05127: NAT10_TcmA_helicase" amino acids 209 to 338 (130 residues), 33.3 bits, see alignment E=1.8e-11 PF01443: Viral_helicase1" amino acids 618 to 671 (54 residues), 21.9 bits, see alignment 5.6e-08 PF13538: UvrD_C_2" amino acids 623 to 670 (48 residues), 42.9 bits, see alignment 1.4e-14

Best Hits

KEGG orthology group: K03581, exodeoxyribonuclease V alpha subunit [EC: 3.1.11.5] (inferred from 100% identity to son:SO_2147)

Predicted SEED Role

"Exodeoxyribonuclease V alpha chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EF46 at UniProt or InterPro

Protein Sequence (712 amino acids)

>SO2147 exodeoxyribonuclease V, alpha subunit (NCBI ptt file) (Shewanella oneidensis MR-1)
MNNATALAANWYNAGALRLKAPLTELLKYWEKERLITALDRHFALEMARLHPNDAQEPLF
MLLCALLSQQLSAQHTCLVLEYIVPTNPMAEPINRCQIRLSLTELIDALQHFDAIGAPNS
NKPLIFEDGRLYLERYHHFETQVASALTRLSAAALSLTPSQPLASDNQSLLQLRRQLDCL
FPSAAHTVEANIDWQKVATATALGNKLAVITGGPGTGKTTTVTKLLLLQQLGTPKQIRLV
APTGKAAARLSESIKASKARLEQELQQASKENPQENQVLLTALSRIPEEASTLHRLLGVI
PNSAHFRHHQGNPLRLDLLIVDEASMVDLPMMYKLLSALPEHAGLILLGDQDQLASVEAG
AVLADICAGLKQASTQHTEWKMRYSQAQAEQLTALTGFNLSHFIHSEPKIGDSLCMLTHS
HRFKGDAGIGLLASAVNRADLAGILSVWQSGLAELTWLEHSVDHSQTQAKISEPSNNTGL
KALLAQACEQYGDYLRLLQPTHATPIHTSEPFCPPSAMEAIAKFNQYRILCAMRTGDYGV
EGINLAVTKALAQAKLIQPQQEFYLGRPIIIQSNDYNLGLFNGDIGLILQDEERADRLMA
HFIKADGKLLKVLPARLPSHETCYAMTVHKSQGSEFNRVALVLPPAPSLVQWQLLTKELI
YTAITRAKQHFSCLGTQQVFERASLQATQRASGLADRLWGDQSLSHTAAVNS