Protein Info for SO2081 in Shewanella oneidensis MR-1

Annotation: ATP-dependent helicase, DinG family (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 PF00270: DEAD" amino acids 29 to 80 (52 residues), 26.8 bits, see alignment 8.3e-10 PF13307: Helicase_C_2" amino acids 456 to 615 (160 residues), 154 bits, see alignment E=8.1e-49

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_2081)

Predicted SEED Role

"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EFA4 at UniProt or InterPro

Protein Sequence (633 amino acids)

>SO2081 ATP-dependent helicase, DinG family (NCBI ptt file) (Shewanella oneidensis MR-1)
MLRAFASDGVLAKHIQGFSARQSQVQMAQIISNAIASKGNAVIEAGTGVGKTFAYLIPAM
LSGKQVIVSTGSKNLQEQLFLKDLPALTAMLGIAPKLALLKGRNNYLCQYRLDRQMQEAS
HIEARLLDDLLKINQWAGMSKDGDIGGLTSVAENSPALPLVVSTKETCLGQRCEFYDACF
TRKARSRAMDAKIIVVNHHLFFADSVLKDTGFAELLPDPDVVIFDEAHLLPDICVSYFGQ
QSSSRTIDDYLQKLLQIYQTELSDTGQIAQFCQRCLAKLSDWHNGLFSIAESDWRVLLGN
KSIALASWDLLAELTALQKLLLAHVGRSELLDDIAVKLAELNHKLNHFFQCDNPQAAYSV
EFGSRFVMLRISPINIARECQQLFVANTSWIFTSATLQVNRSLAHFAKELGISDAKAHIL
DSPFDYPRQALFCVPRQLGNVANQQQALKQLVDVCVKAIEAAQGRTFILFTSHKMLEQTA
LALRTRTQYPLLVQGQAGKQSLLTKFRQLGNAVLLGTSSFWEGVDVRGKLLSCVIIDKLP
FVSPDEPLYRARADNISRQGGDPFTQVSLPQAIIALKQGVGRLIRDEKDCGVLILCDNRI
VNRAYGQAFLNSLPPMARTRDLEQALAFLRQIP