Protein Info for SO2065 in Shewanella oneidensis MR-1

Name: tyrP
Annotation: tyrosine-specific transport protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 395 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 26 to 27 (2 residues), see Phobius details amino acids 39 to 59 (21 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 121 to 139 (19 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 182 to 205 (24 residues), see Phobius details amino acids 218 to 236 (19 residues), see Phobius details amino acids 271 to 296 (26 residues), see Phobius details amino acids 309 to 327 (19 residues), see Phobius details amino acids 333 to 355 (23 residues), see Phobius details amino acids 371 to 393 (23 residues), see Phobius details PF03222: Trp_Tyr_perm" amino acids 3 to 391 (389 residues), 387.4 bits, see alignment E=8.4e-120 TIGR00837: aromatic amino acid transport protein" amino acids 8 to 385 (378 residues), 382.2 bits, see alignment E=1.6e-118 PF01490: Aa_trans" amino acids 8 to 135 (128 residues), 37.2 bits, see alignment E=1.5e-13

Best Hits

Swiss-Prot: 49% identical to TYRP_ECOLI: Tyrosine-specific transport protein (tyrP) from Escherichia coli (strain K12)

KEGG orthology group: K03834, tyrosine-specific transport protein (inferred from 100% identity to son:SO_2065)

Predicted SEED Role

"Tyrosine-specific transport protein" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EFB8 at UniProt or InterPro

Protein Sequence (395 amino acids)

>SO2065 tyrosine-specific transport protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MTQNKFFGSLLLIAGTTIGAGMLALPIASAGLGFGMSSMIMLIFWALMAYTALLMVEIHQ
FAPSDASLNQLARHLLGTKGQVVACIALMFLLYALCAAYIAGGGEQVHQKLTSWLGLALP
PQAGAILFTLLIGTIVGLGTHCVDLINRVLFSLKIIALILMLALLLPQVEGTHLLELPLE
QGLIVSAIPVIFTSFGFHGSIPSVVRYLGIEVKALRKIMLLGSALPLLIYLLWQLGSQGV
LSQSQLMTNQSLSGFISQLASVLHSQYLSSAISVFADLALATSFLGVSLGLFDFIAANLR
QEDNATGRSVTAAITFVPPLGFALFYPQGFITALGYAAIALVILAIFLPVSMVWVQRKQR
DKAKLPQGYRVAGGTLGLVLALLCGLAVISAQLLG