Protein Info for SO2047 in Shewanella oneidensis MR-1

Annotation: prolyl oligopeptidase family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 697 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF02897: Peptidase_S9_N" amino acids 21 to 422 (402 residues), 111.6 bits, see alignment E=4.2e-36 PF00326: Peptidase_S9" amino acids 494 to 696 (203 residues), 159.3 bits, see alignment E=1e-50

Best Hits

KEGG orthology group: K01322, prolyl oligopeptidase [EC: 3.4.21.26] (inferred from 100% identity to son:SO_2047)

Predicted SEED Role

"Prolyl oligopeptidase"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.26

Use Curated BLAST to search for 3.4.21.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EFD4 at UniProt or InterPro

Protein Sequence (697 amino acids)

>SO2047 prolyl oligopeptidase family protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MNRKLLPWCIAGVLTMTAQVHAQEDKYIWLEEVEGAKPMEWVKTQNAASAAEIKAFKGFD
TLVANSLAILNDKERIPYATHIGDKLYNFWKDDTHVRGIYRRTTMEEYAKVDPKWETVLD
VDALGKSESVNWVFKSIDCQYPDNQRCFVSLSRGGADAVEVREFDLTTKDFVPVKEKPFF
LKEAKSSLSWIDKDHAFVGTDFGDGQSMTDSGYPRVVKLWQRGTPLTNAKTIFSGDKTSV
AVSGWVMFDDKTPLSLVTEAHTFYTATQYVYQDGKLIKLPIPQDAEIKGYFQGKLFIELK
SDLATPAATFSQGAVVYANVADLIAQKASFTEFVSPTPTASIAQLSFSKSAIFVNWLDNV
KSKLVRYEQDDKGTWQSMPVPFEANGALTVMDMERDSDDFFVNYTSFLEPSSLYTVNAKA
LKPQKIKGMPQQFAADKFKTKQYFATSKDGTKVPYFVVMAKDLKLDGRNPTLLYGYGGFE
VSLRPAYSATIGKNWLEQGGVYVLANIRGGGEYGPAWHQAALKQNRHKAYEDFEAIAEDL
IARKITSSKHLGIQGGSNGGLLMGAAFTRRPDLYNAVVCQVPLLDMYRFNKLLAGASWMG
EYGNPDIPQEWDYIKTYSPYHNLHKDVHYPKVFFTTSTRDDRVHPGHARKMVAKMKDMGI
DVLYYENIEGGHAGAADNNQAAELNSMAFAYLLQQLK