Protein Info for SO1976 in Shewanella oneidensis MR-1

Annotation: hydrolase, alpha/beta fold family (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 292 transmembrane" amino acids 71 to 84 (14 residues), see Phobius details PF12697: Abhydrolase_6" amino acids 5 to 237 (233 residues), 60.1 bits, see alignment E=1.1e-19 PF00561: Abhydrolase_1" amino acids 7 to 233 (227 residues), 59.4 bits, see alignment E=8.7e-20 PF12146: Hydrolase_4" amino acids 17 to 231 (215 residues), 56.3 bits, see alignment E=6e-19 PF00975: Thioesterase" amino acids 18 to 206 (189 residues), 41.9 bits, see alignment E=2.9e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_1976)

Predicted SEED Role

"FIG084569: hydrolase, alpha/beta fold family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EFJ6 at UniProt or InterPro

Protein Sequence (292 amino acids)

>SO1976 hydrolase, alpha/beta fold family (NCBI ptt file) (Shewanella oneidensis MR-1)
MTTWVLLRGLMRDKRHWNGFDQRLRQRGGTVFTPDLPGNGLLSHQKSPLSIAKYAQAVWQ
QLDENLQGQPFYLLGLSMGGMLAMEMAQQRPWQVKHVFVLNSSAANLSPWYHRFNLFNVL
LAFVKRCRGVQLHPIESTIVRLTSYRHRRDTRLIEHWSEYRKETSPAFSNACRQLYAAFR
YQCPTSLAIPVSILCGDRDALVNMQSSKALAQHFKVELMVLAYCGHDITIDAPAKLVHYL
FDILSSNHGKEELQLVDCADLLDLLDEEIAYHEAKLIQAIPRYSSALPAESE