Protein Info for SO1844 in Shewanella oneidensis MR-1

Annotation: extracellular nuclease, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 948 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00932: LTD" amino acids 22 to 128 (107 residues), 68.2 bits, see alignment E=1.1e-22 PF18911: PKD_4" amino acids 788 to 865 (78 residues), 70.2 bits, see alignment E=1.9e-23 PF00801: PKD" amino acids 794 to 862 (69 residues), 57.1 bits, see alignment 2.2e-19

Best Hits

KEGG orthology group: K07004, (no description) (inferred from 100% identity to son:SO_1844)

Predicted SEED Role

"Extracellular deoxyribonuclease PA3909 (required for catabolism of external DNA)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EFX1 at UniProt or InterPro

Protein Sequence (948 amino acids)

>SO1844 extracellular nuclease, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MFKHKTLLALAISSVCGFAHGADNLIISEYVEGSGNNKAIELYNPTSSSIDLSQYQLRFY
FNGSTNVGSTISLNGTLAAGATYVVADNDASADILAVTNQQSSASFFNGDDAIVLTHQNQ
VIDSLGQVGVDPGSEWGSGDLSTQDNTLRRNPDQLIADPIIDDAVTFNTWLGFAKDDIAD
LGKFSVGTPTDPVDPPPSSLACGEASTAIHVLQGSTNASPLNGQTLVVEAIVVSNQEAGL
KGIFVQMADNEADNDPQTSEGVFVYTGTAPTGYVAGDRVRLKAKVTEYQGLTELTTVADH
KLCVAGQALPSAAVVTLPVNTSDDFEPFEGMRVRFSQDLVVNEVYKLGRYGEILLGSRRH
FIGTQVAAPGADALAVTAANQKDSILLDDGLTAQNPDPVIFPAPGLSASNTVRVGDKATA
LTGVMHYGFNLYRIMPTESITFVAENPRPQSPVLAEGGNLKVASFNVLNYFNGDGQGSGF
PTARGANTLSEFERQKTKIISAMVGIGADVFGLMEIENDGFGANSAIADLVAGLNTAVGE
NRYAYVIPKINGNNLSAIGTDAITVGLIYRSDKVSPQGDARILSSTNSPLDETGQPLFDD
GKNRPMLTQAFVLNGSEEALVVAVNHLKSKGSECAGDPDVNDGQGNCNITRTRAATAAGQ
WIAAQYPEQGVLLIGDLNAYAKEDPLTALANTGFSELFAKLEKANAYSYVFSGESGQLDH
ALANAALVDKVVDVTEWHINTDEPRVLDYNEEFKTPTQVQDLYASDAYRSSDHDPVVISL
LLEAEKVAPEASFTKVVNGASVQFTSTSTDSDGQIVSAQWDFGDNSQGIGEAVSHTYAQS
GDYLVTLTVTDNDGLSHSSSQMVTVVVENVKKPPVAQIQRINLWLVDMFISTSYDTDGVI
KQHKWKFDNGTRANGPVVLRLARRGEHTVELTVKDNDKLTDTTTLTYR