Protein Info for SO1457 in Shewanella oneidensis MR-1

Annotation: type I restriction-modification system, M subunit, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 684 PF13588: HSDR_N_2" amino acids 33 to 101 (69 residues), 30.9 bits, see alignment E=3.7e-11 PF02384: N6_Mtase" amino acids 309 to 598 (290 residues), 113.6 bits, see alignment E=1.8e-36

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_1457)

Predicted SEED Role

"Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EGY1 at UniProt or InterPro

Protein Sequence (684 amino acids)

>SO1457 type I restriction-modification system, M subunit, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MTTDNDKKQQEVLAIEDGMMLDYLTNNPIKETPKELVRQKTLRALFHEYGLSAEDMALDF
NTTVGGKRKKIDIAIFEHGAEHLSENIRRIVICDKEPIKGKKSAVKMRDHDQAQKDLQLM
EDMMREQVGDKYVLEKCHWGLWTNGIEFFFVEKEESRFDTKFNAVGDWPLADETLGSRDV
ASNAQLRTADREMLLTAFRRCHNFIHGNEGMPKDAAFWQFLYLIFSKMYDERIGNRDREF
WASPTEQFDDEGRKKIRARINPLFEKVKKAYPEIFSGNEEIILSDRALAFMVSELAKYDF
TRTEMDAKGAAYQEVVGDNLRGDRGQYFTPRGAIKLIVEMMAPQPHEKVLDPSCGTGGFL
EQTLSFINRKLCEEEEVKLGAETTEEFISIQQQIKKFAENNLFGCDFDPFLCRASQMNVV
MASNAMANIYHMNSLEYPHGHLKGVEPAKSKIPVGDSSGKDGSIDVILTNPPFGSDIPVT
DKQILEQYDLAYVWERTENGGFRKTERRKDAVSPEILFIERCVQWLKQGGRMGIVLPDGI
LGNPGDEYIRWWLMQECWVLGCVDLPVESFIVEANVNILTSLLFLKKKTDTEKDAIAFGG
EPEYPVFMAVAEKVGFDRRGNTLYERHPDGEEKVIEEDVEERIRINGQNVVRKLKRRSKI
LDDDLPKIAKAWKEFRANNPEPSV