Protein Info for SO1230 in Shewanella oneidensis MR-1

Name: torS
Annotation: sensor histidine kinase/response regulator TorS (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1025 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details transmembrane" amino acids 372 to 395 (24 residues), see Phobius details amino acids 586 to 605 (20 residues), see Phobius details TIGR02956: TMAO reductase sytem sensor TorS" amino acids 10 to 1020 (1011 residues), 1336.4 bits, see alignment E=0 PF00672: HAMP" amino acids 396 to 441 (46 residues), 26.5 bits, see alignment (E = 1.6e-09) PF00512: HisKA" amino acids 507 to 572 (66 residues), 61.8 bits, see alignment 1.3e-20 PF02518: HATPase_c" amino acids 619 to 728 (110 residues), 84.1 bits, see alignment E=2.4e-27 PF00072: Response_reg" amino acids 750 to 860 (111 residues), 46.7 bits, see alignment E=8.2e-16 PF01627: Hpt" amino acids 932 to 1019 (88 residues), 43.7 bits, see alignment E=6.8e-15

Best Hits

KEGG orthology group: K07647, two-component system, OmpR family, sensor histidine kinase TorS [EC: 2.7.13.3] (inferred from 100% identity to son:SO_1230)

Predicted SEED Role

"Sensor protein torS (EC 2.7.3.-)" in subsystem trimethylamine N-oxide (TMAO) reductase (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EHJ1 at UniProt or InterPro

Protein Sequence (1025 amino acids)

>SO1230 sensor histidine kinase/response regulator TorS (NCBI ptt file) (Shewanella oneidensis MR-1)
MAPLSLSRRSLTGRLMLAFSVLGLLLLLLVSLGSLSLHWLKQADRYLYEESLPASQAARQ
LVQASNALSDGVTQLGQVEDERQREFIGRKLNLESATMLNSIKVLLALDVNEDNHLPVLA
GQIIEQLTLLGQSVGQRITLGDELQRRARELSVAAAHASELLQSELAVVDSAILAKLSQA
YPDMAGNKRSGQLLDDVIERELDIQEQLNRALKLVHQIALLSQLFEVSELQSELQLSVPR
LLATFASTLPSHPVAHINQQKGTAIEQASEAVTELSAPEVGIDLMALTTVSELIRDPGRL
NALKAELVTLKHTPKIIKLQRDLSQSLQRQQRQQQALAEKLYSLNTLVDSALNQQQQRAE
LARSDYLMQLSYARFGLLATGMLMFVIMGWVIYRVIYRGIALRLNQATQAMSRLSLGDIN
VSLDARGDDELTAMANAIEAFKRKTAHNLKLQADLRQVADELTEHKKALEQTVATRTQEL
AETNLRLDAEAKGHAKARVVAEEASQAKSQFLATMSHEIRTPLNGLLGTLTLLGQSQLPP
AQQQMLALSQYSGTLLQTVLSDILDFSRLEQGNLTNEPRPTDINALLDEVLAIMVAGANL
AGLSLRLNRPQLPACINIDGPKLRQVLFNLIGNGIKFTSEGSVSLNVSLQGGRLAFVVAD
TGVGIAPEVREQLFIPYSTLPNQGRSRGTGLGLAICKQLVELMDANGRGIWVKSEPGKGS
EFGFELCFTQCDKAQDAQTLVHKQVHTQRVLVVEDNKVNAMVAQGFLAHLGHSSTLAASC
QLALECVSADKAFDAVMLDIQLSDGSGVALLPQLKALFGAKNVKFAAFTAQMQMEDLSLY
REVGFDTVLAKPLSLQTLTQWLGVAMASSSLETESPGLSASPSFISASSAPLAQATDTSG
AIPLGNQATETLLDIEQLQQDIEVLGVKAVSDMLALYKTSSAEQIERLSEATFVESSADS
AKLLHALKGSSASMGLKALTQCCQVWEKQLKTTGAQKLEIQSANELRACWLASMTALEQW
LVTVE