Protein Info for SO1125 in Shewanella oneidensis MR-1

Annotation: integral membrane domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 transmembrane" amino acids 7 to 29 (23 residues), see Phobius details amino acids 35 to 55 (21 residues), see Phobius details amino acids 71 to 92 (22 residues), see Phobius details amino acids 100 to 119 (20 residues), see Phobius details amino acids 128 to 149 (22 residues), see Phobius details amino acids 156 to 174 (19 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 215 to 236 (22 residues), see Phobius details amino acids 246 to 265 (20 residues), see Phobius details amino acids 271 to 290 (20 residues), see Phobius details PF00892: EamA" amino acids 7 to 142 (136 residues), 61.3 bits, see alignment E=5.6e-21 amino acids 156 to 286 (131 residues), 54.3 bits, see alignment E=8.1e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_1125)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EHT8 at UniProt or InterPro

Protein Sequence (306 amino acids)

>SO1125 integral membrane domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MKASNLAYVYGMAAVFLWSTVATAFKIALGFYSPLQLVFVAVLTSIVTLGAILTWQKKLP
LLKVQLLRRPTFYLVTGLINPFLYYVVLFKAYSLLPAQQALSLNYTWAVLLPLLAAPLLK
QHLRKSDMIAALIAYSGVFIIATGGDVSGFRFDSPLGIGLALTSTLLWCLYWIVNTKDQG
DPVVSLLLSFLIGLPFITITLLLTDALPSFSIKAVMAGMYVGLFEMGITFVLWLMALKTA
TRTANISTLVFLSPVMSIGFIAWILQETIATATYIGLGFILAGMMLQQLFPRYLERKTKL
NTKLAE