Protein Info for SO1001 in Shewanella oneidensis MR-1

Name: chaA
Annotation: calcium/proton antiporter (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 35 to 57 (23 residues), see Phobius details amino acids 71 to 93 (23 residues), see Phobius details amino acids 106 to 127 (22 residues), see Phobius details amino acids 141 to 160 (20 residues), see Phobius details amino acids 172 to 190 (19 residues), see Phobius details amino acids 219 to 239 (21 residues), see Phobius details amino acids 250 to 270 (21 residues), see Phobius details amino acids 287 to 310 (24 residues), see Phobius details amino acids 316 to 336 (21 residues), see Phobius details amino acids 344 to 362 (19 residues), see Phobius details PF01699: Na_Ca_ex" amino acids 42 to 192 (151 residues), 68.6 bits, see alignment E=3e-23 amino acids 221 to 362 (142 residues), 37.4 bits, see alignment E=1.2e-13

Best Hits

Swiss-Prot: 46% identical to CHAA_ECOLI: Sodium-potassium/proton antiporter ChaA (chaA) from Escherichia coli (strain K12)

KEGG orthology group: K07300, Ca2+:H+ antiporter (inferred from 100% identity to son:SO_1001)

MetaCyc: 46% identical to Na+/K+:H+ antiporter ChaA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-101; TRANS-RXN-42

Predicted SEED Role

"Ca2+/H+ antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EI49 at UniProt or InterPro

Protein Sequence (365 amino acids)

>SO1001 calcium/proton antiporter (NCBI ptt file) (Shewanella oneidensis MR-1)
MKTFIKDEFALLLGILTLVFFKTGGDSLLADGTALSTYIPVSLALLGVVTWAIFSVVRHS
DALAIKLGDPYGTLILTLSVISLEVVMISSVMLTGEPNPVMARDTMFAVVMIITNGLVGF
TLLLGGWRYHTQHFNLDGVKSYLVAIIPLALLCLVLPNFTEGGTVGGMSKPMSWMLIIIS
ILLYGIFLVVQTKSHSHFFVDADNEDHEEHHGILRSNIYHTLLLIGYLLVVILLAKTLAM
PINYSVASLGAPPALGGFVVACLILSPEAVGGFKAALNNQLQRAMNLYFGSVLATIALTV
PAVLIVGSVINQEVHLGLSAADMVLLATTLMVCKVSFSSGRTNALHGATHLVLFIVYLFL
MFEHA