Protein Info for SO0990 in Shewanella oneidensis MR-1

Annotation: urease domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 563 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF07969: Amidohydro_3" amino acids 74 to 558 (485 residues), 391.3 bits, see alignment E=1.1e-120 PF01979: Amidohydro_1" amino acids 232 to 557 (326 residues), 68.6 bits, see alignment E=5.9e-23

Best Hits

KEGG orthology group: K07047, (no description) (inferred from 100% identity to son:SO_0990)

Predicted SEED Role

"urease domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EI59 at UniProt or InterPro

Protein Sequence (563 amino acids)

>SO0990 urease domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MKNKQSKSLLIKSMALTGLFTISACANEELADTLLTNTNIYGHNNATSLAIKDGKIVYIG
DEQNAMNHVSNKTQVIDLKGGYLLPGFVDNHNHVFEAASEIGSDCLLDEDKDINGYIRSL
RACKEELEEGEWLLGYGHELSQLMQDNDTSPLAILDEIFPNNPVIIMEQTSHSMWVNSLA
LAEAGITIHSKEPQGGKILKDKTTGKLLGILLDNAGDLLMEQAWKNQPNLAEANYQGLLN
GLAQASKHGITTIGDGRLYWKRGWLETWLTAEKNQALTARVSLRPWVYPADEANEQLAFF
KKIKSNDKQRLIQINQVKIYSDGIIINGTASTLDPYDWSYTPQIPHGLEYIPATKMAWWL
SELNKIGYGAHIHAIGDAGVRNTLNAIETLRAQGATTAYSMTHLEMVSAQDIKRFAPLRV
DADFQLGSDYIAEQDHDWAIPFIGKQRAHALLPINAILNTGANVTLSSDWNVNDINPLVG
IANAVYLKNMGIADIHQAIAAYTINPAQALGLDDITGTLEVGKSADIVMLERDITQSTPK
QIANTRVLMTWLEGEVVYDEQTE