Protein Info for SO0880 in Shewanella oneidensis MR-1

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 327 PF12146: Hydrolase_4" amino acids 56 to 270 (215 residues), 40.7 bits, see alignment E=1.7e-14 PF00561: Abhydrolase_1" amino acids 57 to 300 (244 residues), 64.2 bits, see alignment E=1.5e-21

Best Hits

KEGG orthology group: K07019, (no description) (inferred from 100% identity to son:SO_0880)

Predicted SEED Role

"Hydrolase, alpha/beta fold family functionally coupled to Phosphoribulokinase" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EIF9 at UniProt or InterPro

Protein Sequence (327 amino acids)

>SO0880 conserved hypothetical protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MPNAFTPPWWAKSPHVQTILPVFTKVAKPVLERQRLELPDGDFIDLDWQAPPKVGKPIVV
IIHGLEGSAQSHYARRILQACKTQGLAAVVHHHRSCSGEANRLARSYHSGDTDDLQFSLS
LLQQTYPQSPLLAVGYSLGGNVLTKYQGEYQDQSLLTRAVVVSAPLQLSACAKRLEHGFS
TVYQSHLVKQLQHKVNQKLTAPDLAGTMSLTPKQVANLNTFYDFDDKVTAPLHGFLGVED
YYTRASGLPYVNRITKPTLILHALDDPFMTDEVIPHPSQISEHVEYELHAHGGHVGFIEG
GTPWKPRYYLERRILDFLLANDASSAP