Protein Info for SO0859 in Shewanella oneidensis MR-1

Annotation: sensory box histidine kinase/response regulator (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1765 transmembrane" amino acids 13 to 35 (23 residues), see Phobius details amino acids 307 to 329 (23 residues), see Phobius details PF13426: PAS_9" amino acids 406 to 506 (101 residues), 21.3 bits, see alignment 1.4e-07 amino acids 522 to 629 (108 residues), 36.8 bits, see alignment 2.1e-12 amino acids 665 to 738 (74 residues), 25.3 bits, see alignment (E = 7.8e-09) amino acids 917 to 1018 (102 residues), 41.8 bits, see alignment 5.7e-14 TIGR00229: PAS domain S-box protein" amino acids 515 to 636 (122 residues), 60.5 bits, see alignment 8.9e-21 amino acids 639 to 764 (126 residues), 41.6 bits, see alignment 6.2e-15 amino acids 792 to 899 (108 residues), 30.5 bits, see alignment 1.8e-11 amino acids 902 to 1023 (122 residues), 61.9 bits, see alignment 3.3e-21 PF13188: PAS_8" amino acids 516 to 567 (52 residues), 29.5 bits, see alignment (E = 2.6e-10) PF00989: PAS" amino acids 516 to 572 (57 residues), 27.9 bits, see alignment (E = 1e-09) amino acids 905 to 1013 (109 residues), 40.1 bits, see alignment 1.6e-13 PF08447: PAS_3" amino acids 667 to 753 (87 residues), 69.4 bits, see alignment 1.3e-22 amino acids 800 to 882 (83 residues), 45.8 bits, see alignment 3.1e-15 amino acids 927 to 1005 (79 residues), 28 bits, see alignment (E = 1.1e-09) PF08448: PAS_4" amino acids 915 to 1020 (106 residues), 23.4 bits, see alignment 3e-08 PF00512: HisKA" amino acids 1039 to 1104 (66 residues), 83.2 bits, see alignment (E = 5.3e-27) PF02518: HATPase_c" amino acids 1151 to 1265 (115 residues), 97.7 bits, see alignment 2.8e-31 PF00072: Response_reg" amino acids 1284 to 1392 (109 residues), 87.9 bits, see alignment 2.6e-28 amino acids 1426 to 1536 (111 residues), 93.1 bits, see alignment 6.2e-30 PF01627: Hpt" amino acids 1598 to 1672 (75 residues), 38.1 bits, see alignment (E = 7.2e-13)

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_0859)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EII0 at UniProt or InterPro

Protein Sequence (1765 amino acids)

>SO0859 sensory box histidine kinase/response regulator (NCBI ptt file) (Shewanella oneidensis MR-1)
MDKSKLRTFRSKILSHIALPLILIMATVYGITSWFNYLSIEKRLYENLAQESSHSASRLQ
FLLEHAQANTQGLSDFIGLLADKDDINNPEKLKTVLTNRIQRNPDFFGSAIAFKPNTFPN
KKLFSPYVYRSGSGFNYLDIGADGYDYTDGNWDWWSKAINQVGGYWSKAYFDEGAGNVLM
ITYAVPFGVQPDYFGVTTVDLALDRLPEQLGIAPSRLVVLDDQGRLIFHSDKEKVLAASS
SGWLDKQNIKNIAFATLLNDGQAGQASFVDDKGTVYLASVAEVAKLKWRVVVMVPKHELF
ASLLDDIASAILNLSLLTLLLLLTCYIAAKRLTRPLEALESGILAFGQGKAQELTIPKGA
VSEIVTLSETFNQMAALLAEREQAILDSRGNRFARLIDGMSDKSFYCSLDPDGQLAQVSE
GVTKVLGIPPELLKRKYQRLFSANPLNEKNWEYTDLALKGQNVPPHQIELVDAKGQARRL
DVFMQPLVSDTGELMSVEMLFTDVTEQFSAAAWSNAVLEAAPEAMLIVDQNGQIVFSNSR
CQQLFGYDAKAMLALQIETLLPEELRHLHTGERLDFLREGRDRPMASARHVRALKSDGGE
FVAEIALSILPSDFDGRRQVAASIRDMTQKIMVEQKIRDSELRFRGLVTNIPGAVYRTRI
GEVWVIEYVSDNIAEITGYAASQFIENRQRTFTSLILEDDRALCNQHIERALAQQETFEV
EYRIRHRDGSIRWVHEKGKASYSEEGLPLWFDGSIDDVTESKLAIDEIEASRQQLTNITE
SIPCTVYQLRWVSPTDRSFTFLSGAALAMLGLHREELLRDFNIIAERIFDEERPEVISAL
AGKSDDQLRWIREFRYRHPNGGIRWMEAGASGHYADDGSIIWNGYVMDVTERKSIEEELA
VSEAHFKALFDGATIGIVNVDIKGLILDCNYQFCEDMGLSRDELRSTPIFDVLSAQDKDV
AKAQFKELVEGKIDHYRGERSFVRPSGEPLWMTVNVSTLLDSQNQFESAVVSMVDMTELK
LLSDELLVAKDEADAASKAKGDFLANMSHEIRTPMNAIIGMSQLCLQTQLDKKQKNYLEK
IERASQSLLSIINDILDFSKIEAGKLDIENVSFQLDTMLEDLSDMFSERAAQKQIELLFA
VAPNVPRHLLGDPLRLGQVLINLMNNAIKFTERGEVLLSLSLVEQQNDDVVLRFSVRDSG
IGLTQEQQSKLFKSFTQADTSTTRKYGGTGLGLAISKQLVELMGGSIGVESQLGHGSTFF
FTVKLCISSGQKLFVGQELDGMSILVADDNATARDIMRTTLESMGFNVDTVRSGDEAIMR
CSQQEYAVALIDWKMPNLDGIETAKQIKQQTKNAPRILMVSAHANQDFLTQIEQLGLAGY
ISKPISASRLLDGIMNALGRSGILPVRRHQDNIAPELLLPLKGKRILLVEDNEMNLEVAT
EFLEQVGIILSIATNGQIALDKLAQQSFDLVLMDCQMPVMDGYQATKAIRQRPELAQLPV
IAMTANAMAGDKEMCLRAGMNDHIAKPIEVNLLYQTLLKYLGAPVPSLENAEFVVNESLN
PLNLDVESVVKWPEHPELDIDRGLQLVQNSKRLYQRIFDRFATSQRNVVDQINKALASNK
REDAVRMAHTLKGLAGNLSSSKLAELARQLELHLSENADYQVELDQIQILVASICEAIEK
AKPQFEETSTSTAEHLPKDALIAALKQLRQSLEDADSDAVTQMDALKPQMSALLWQQLSP
ALTMINQYQFDEAVDLIDEVLAKLT