Protein Info for SO0577 in Shewanella oneidensis MR-1

Annotation: sensory box histidine kinase/response regulator (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1188 transmembrane" amino acids 306 to 325 (20 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 409 to 530 (122 residues), 53.9 bits, see alignment E=9.9e-19 amino acids 533 to 659 (127 residues), 36.6 bits, see alignment E=2.1e-13 PF13188: PAS_8" amino acids 411 to 459 (49 residues), 30.9 bits, see alignment (E = 7.5e-11) PF00989: PAS" amino acids 411 to 520 (110 residues), 45.9 bits, see alignment E=2.1e-15 PF08448: PAS_4" amino acids 416 to 524 (109 residues), 63.8 bits, see alignment E=6.8e-21 PF13426: PAS_9" amino acids 420 to 521 (102 residues), 33.7 bits, see alignment E=1.5e-11 amino acids 556 to 651 (96 residues), 24 bits, see alignment E=1.5e-08 PF08447: PAS_3" amino acids 558 to 647 (90 residues), 73.7 bits, see alignment 4.8e-24 PF00512: HisKA" amino acids 674 to 738 (65 residues), 80.1 bits, see alignment 4e-26 PF02518: HATPase_c" amino acids 785 to 899 (115 residues), 96.4 bits, see alignment E=5.8e-31 PF00072: Response_reg" amino acids 922 to 1036 (115 residues), 70.3 bits, see alignment E=6.1e-23 amino acids 1066 to 1177 (112 residues), 91.1 bits, see alignment E=2.1e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_0577)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1188 amino acids)

>SO0577 sensory box histidine kinase/response regulator (NCBI ptt file) (Shewanella oneidensis MR-1)
MEQREEQVERHVLQIDLLLESSIRAVKSLRDVAVDHLRLGELVRKERLPQYGKFNESGQY
FTLEPNYAKGGKPFTNMGRITGAGSLDGRSDKFYQELEMLFELSLSFPVAKEAAPKASAI
YYLSRQRMMSYFPWTNDDERFRDELLNKKQFQYATPAMNPQRSVFWSEAYVDSTGKGLLT
TLGVPVYLDDEFMGSINLDMTLASLARQIRVYFKMPGTVILLDQQNNILSHSDFDGSDIN
RVYHISQRIPSELHSLPESELFDAHEGIIRNGYYIHSVALHNAPWRLLYLQNEDDLFQDS
VEKLQLTFILVVIALSVLVTIVHWQTRRSFVSPASRLLSHLEGCSQEPRKPPEKITPGWE
PWFLLVSRIFEENKQYTHHLAEQNKRLDKLVARRTERLKDATERREREYALLRSLLDSIP
EAIVFKDKEGNYLGCNKAAERMLGYTESEMIGLSSEDLTSPEMGIRIRAEDAQILKDRTP
LRYQEKVELAGKPVLLDTLKLPFYNRRGELQGLIAVWRDVTREYESAEQLRLSEERYHLA
MDAVEDGLWDWYLDSEHIICNPSYYSMLGYKPNEFPALVSAIDQLTHPDDRIRVEEYRNQ
YLENPVDAYEIEFRILGKNSSYHWVLSRGRVVEFTTDGQPKRMVGTHKDITRHKSNEVAL
LEAKQDAELANLYKSEFLANMSHEIRTPMNAIIGMLQLAQRTSLTAQQKDYLEKAGFSAQ
SLLRIINDILDFSKIEAGKLELERVPFPLDKVLDHALDLNALKAQEQGVELLLYAPVTAG
LILKGDPLRLGQVLINLLSNAVKFTQSGEIELGCEDVGERDHRITLKFWVRDTGIGISKD
QQEKLFDAFAQADGSTTRKYGGTGLGLSISKHLVSMMGGKMQVQSELGVGSTFSFTISFE
IAEEAKIEPLVVPEKLNNLRTLVVDDNPTALQIYSALMRDFHFEVDTAASGAEALYKLSR
DPIDLLLLDWMMPEMDGSDVISAIDTMVAEGRIAKRPIIIMMTAYAAEPLLHEVDSANVF
AVLQKPFKASSLFDEIIAAFADEPRLNVVQPIAEVAVEEGEHTGLVLLVEDNFINQQVAT
ELLKSAGYEVVVAGNGQIALDIVDSRPFDAVLMDIQMPVMDGLTAARALRERYSADVLPI
IAMTAHAMSGDREKSLAAGMNAHITKPIVLTELFETLTHWIKHKHNHR