Protein Info for SO0300 in Shewanella oneidensis MR-1

Annotation: lipoprotein, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 619 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF04348: LppC" amino acids 47 to 614 (568 residues), 398.7 bits, see alignment E=2.3e-123

Best Hits

Swiss-Prot: 32% identical to LPOA_VIBAE: Penicillin-binding protein activator LpoA (lpoA) from Vibrio antiquarius (strain Ex25)

KEGG orthology group: K07121, (no description) (inferred from 100% identity to son:SO_0300)

Predicted SEED Role

"LppC putative lipoprotein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EK06 at UniProt or InterPro

Protein Sequence (619 amino acids)

>SO0300 lipoprotein, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MLKSLNTTKFVSVAILSAVLAGCGSQAPTSTNTAPTVATSLASAPLAPNVYLAQAANSKD
PQQRDTYLLLAAHSYINANDYAAAQKLLKPMLPSLTQIPTLVAEHKYLTARVLEHTSTPL
DALKTLTYPSTWVLPGWQMAAYHQLRAHLFQLNKQPIDQVRELSLLTTYLPPAEASEVNN
QIWQVLQPMHEQTLLEFTKDAKSPVFAGWLQLAYIAKHYAVDPNQLVRYLGDWQKQNPYH
PAAAKLPADLDHALNAKPYTPKNIAVLLPLTGQRASAANAIRQGILASYLAKPNEQVSVN
FYDTANDAVSAYQQAVNAGAEFIIGPLLPNEIDQLLALNTSATPTATAPAASAPIPQLFL
NQTDKFAPDANKFYFALSPAQEAADAATRMYQDGVTMPLLLASNDAIGKRMAESFIQAWK
KKSDAPIEVYYYDGGDKMKTTVQDALGVRDSQARIARIKELLGNSVQADFRSRQDIDAIY
MISTPQELTLLKAFIDVTFSVFTQPVPLYTSSRSRIDNESSQTAQDLNNLTLSDAPWLMQ
NSEENLMVNTLWPGWNNGQKRLFVMGYDAMDLISKLAQMRSFTGYQFNGRSGVLSVNPDG
VINRQLSWGRYQRGSFRQL