Protein Info for SO0197 in Shewanella oneidensis MR-1

Annotation: fatty acid desaturase, family 1 (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00487: FA_desaturase
  • amino acids 39 to 260 (222 residues), 81.4 bits, E=4.8e-27

Best Hits

KEGG orthology group: K00507, stearoyl-CoA desaturase (delta-9 desaturase) [EC: 1.14.19.1] (inferred from 100% identity to son:SO_0197)

Predicted SEED Role

"Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1)" (EC 1.14.19.1)

MetaCyc Pathways

• oleate biosynthesis II (animals and fungi) (1/2 steps found)
• palmitoleate biosynthesis IV (fungi and animals) (1/2 steps found)
• sorgoleone biosynthesis (2/8 steps found)

KEGG Metabolic Maps

• Biosynthesis of unsaturated fatty acids

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.19.1

Sequence Analysis Tools

See Q8EK98 at UniProt or InterPro

Protein Sequence (368 amino acids)

>SO0197 fatty acid desaturase, family 1 (NCBI ptt file) (Shewanella oneidensis MR-1)
MKKPPIIWLNVILFSLTFLSAVILVPWYGIVYGYGASEWIAFVVLAFASGLSITAGYHRL
WSHKAYKTHPAIRFLYALGGALALQNSALHWASDHRVHHKHVDDNDKDPYSAKMGFWYSH
IGWMLREYQAQRYHDYQNVRDLQNDRIVMWQHKHYLTLVLLMNIGLPALLGWFTGNIAGM
LLMAGLLRLVVVHHCTFFINSLAHVWGCQPYTDKNTARDNGFLAVLTYGEGYHNFHHIFE
NDYRNGIKWWHYDPTKWLIKSLSWVGLAKDLRTSPQERIESARLQMQLLHAKNKVLNLPN
ADEIIEKIQQEYELMKQHLLEYYQAQKTLLEAKRKQLVDQQLLQQVEELKTRFLNQQKSW
KSLTATYS